Results 1 to 10 of about 9,648,893 (334)

Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL CE by cells expressing scavenger receptor B-I

Journal of Lipid Research, 1999
The transport of HDL cholesteryl esters (CE) from plasma to the liver involves a direct uptake pathway, mediated by hepatic scavenger receptor B-I (SR-BI), and an indirect pathway, involving the exchange of HDL CE for triglycerides (TG) of TG-rich ...
Xavier Collet, Alan R. Tall, Humaira Serajuddin, Karim Guendouzi, Lori Royer, Helena Oliveira, Ronald Barbaras, Xian-cheng Jiang, Omar L. Francone   +8 more
doaj   +1 more source

Biogenesis of Mitochondrial Metabolite Carriers

Biomolecules, 2020
Metabolite carriers of the mitochondrial inner membrane are crucial for cellular physiology since mitochondria contribute essential metabolic reactions and synthesize the majority of the cellular ATP. Like almost all mitochondrial proteins, carriers have
Patrick Horten, Lilia Colina-Tenorio, Heike Rampelt   +2 more
doaj   +1 more source

Lipid carrier proteins and ethanol

Journal of Biomedical Science, 2001
Ethanol has a pronounced effect on lipid homeostasis. It is our overall hypothesis that certain lipid carrier proteins are targets of acute and chronic ethanol exposure and that perturbation of these proteins induces lipid dysfunction leading to cellular pathophysiology. These proteins include both intracellular proteins and lipoproteins.
W G, Wood, N A, Avdulov, S V, Chochina, U, Igbavboa   +3 more
openaire   +2 more sources

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology

Physiology, 2020
Members of the mitochondrial carrier family (SLC25) transport a variety of compounds across the inner membrane of mitochondria. These transport steps provide building blocks for the cell and link the pathways of the mitochondrial matrix and cytosol.
Edmund R. S. Kunji, M. King, J. Ruprecht, C. Thangaratnarajah   +3 more
semanticscholar   +1 more source

Structural informatic study of determined and AlphaFold2 predicted molecular structures of 13 human solute carrier transporters and their water-soluble QTY variants

Scientific Reports, 2022
Solute carrier transporters are integral membrane proteins, and are important for diverse cellular nutrient transports, metabolism, energy demand, and other vital biological activities.
Eva Smorodina, Igor Diankin, Fei Tao, Rui Qing, Steve Yang, Shuguang Zhang   +5 more
doaj   +1 more source

Random and combinatorial mutagenesis for improved total production of secretory target protein in Escherichia coli

Scientific Reports, 2021
Signal peptides and secretory carrier proteins are commonly used to secrete heterologous recombinant protein in Gram-negative bacteria. The Escherichia coli osmotically-inducible protein Y (OsmY) is a carrier protein that secretes a target protein ...
David Gonzalez-Perez, James Ratcliffe, Shu Khan Tan, Mary Chen May Wong, Yi Pei Yee, Natsai Nyabadza, Jian-He Xu, Tuck Seng Wong, Kang Lan Tee   +8 more
doaj   +1 more source

Enhanced production of polyunsaturated fatty acids by enzyme engineering of tandem acyl carrier proteins

Scientific Reports, 2016
In some microorganisms, polyunsaturated fatty acids (PUFAs) are biosynthesized by PUFA synthases characterized by tandem acyl carrier proteins (ACPs) in subunit A. These ACPs were previously shown to be important for PUFA productivity.
S. Hayashi, Y. Satoh, Tetsuro Ujihara, Y. Takata, T. Dairi   +4 more
semanticscholar   +1 more source

Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer [PDF]

Einstein (São Paulo)
Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins,
Natália Gregório Custódio, Fábio Ribeiro Queiroz, Angelo Borges de Melo Neto, Brenda Martins Cavalcante, Laurence Rodrigues do Amaral, Telma Maria Rossi de Figueiredo Franco, Matheus de Souza Gomes, Vasco Ariston de Carvalho Azevedo, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Wander de Jesus Jeremias   +10 more
doaj   +1 more source

Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]

Jichu yixue yu linchuang, 2021
Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
doaj  

Transport proteins (carriers) of mitochondria [PDF]

IUBMB Life, 2008
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
openaire   +2 more sources