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Moco Carrier and Binding Proteins

open access: yesMolecules, 2022
The molybdenum cofactor (Moco) is the active site prosthetic group found in numerous vitally important enzymes (Mo-enzymes), which predominantly catalyze 2 electron transfer reactions. Moco is synthesized by an evolutionary old and highly conserved multi-
Tobias Kruse
doaj   +4 more sources

ER targeting of non-imported mitochondrial carrier proteins is dependent on the GET pathway [PDF]

open access: yesLife Science Alliance, 2021
The GET pathway is required to target non-imported mitochondrial carrier proteins to the endoplasmic reticulum, which prevents their deposition into Hsp42-dependent protein foci.
Tianyao Xiao   +2 more
doaj   +2 more sources

Mitochondrial carrier proteins [PDF]

open access: yesFEBS Letters, 1994
Ten mitochondrial carriers have been purified from animal mitochondria. They are small proteins with a molecular mass ranging from 28 to 34 kDa on SDS‐PAGE. So far, five of these proteins have been sequenced. Their polypeptide chain consists of three tandemly related sequences of about 100 amino acids.
exaly   +3 more sources

Carrier Proteins Facilitate the Generation of Antipolysaccharide Immunity via Multiple Mechanisms [PDF]

open access: yesmBio, 2022
Capsular polysaccharides (CPSs) are important antigenic targets against bacterial infections. As T-independent antigens, however, CPSs elicit short-lived immune responses in adults and are poorly immunogenic in young children.
Fan Zhang   +4 more
doaj   +2 more sources

Structure, function and dynamics in acyl carrier proteins. [PDF]

open access: yesPLoS ONE, 2019
Carrier proteins are four-helix bundles that covalently hold metabolites and secondary metabolites, such as fatty acids, polyketides and non-ribosomal peptides.
Rohit Farmer   +2 more
doaj   +2 more sources

Predicting substrates for orphan solute carrier proteins using multi-omics datasets [PDF]

open access: yesBMC Genomics
Solute carriers (SLC) are integral membrane proteins responsible for transporting a wide variety of metabolites, signaling molecules and drugs across cellular membranes. Despite key roles in metabolism, signaling and pharmacology, around one third of SLC
Y. Zhang, S. Newstead, P. Sarkies
doaj   +2 more sources

Presentation matters: Impact of association of amphiphilic LPS with serum carrier proteins on innate immune signaling. [PDF]

open access: yesPLoS ONE, 2018
Recognition of Pathogen-associated Molecular Patterns (PAMPs) by Toll-like receptors is central to innate immunity. Many bacterial PAMPs such as lipopolysaccharide (LPS) and lipoteichoic acid have amphiphilic properties. The hydrophobicity of amphiphilic
Loreen R Stromberg   +5 more
doaj   +2 more sources

A guide to plasma membrane solute carrier proteins [PDF]

open access: yesFEBS Journal, 2021
Ariel Bensimon, Giulio Superti-Furga
exaly   +2 more sources

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