Results 31 to 40 of about 6,901,957 (346)
Legionella pneumophila secretes a mitochondrial carrier protein during infection.
PLoS Pathogens, 2012 The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal +16 more
doaj +1 more source
A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms
Food Innovation and Advances, 2023 Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao +6 more
doaj +1 more source
Engineering an AB5 Protein Carrier [PDF]
Scientific Reports, 2018 AbstractThe promise of biologic therapeutics is hindered by the challenge to deliver their activity to biochemically relevant sites within diseased cells. The favourable application of the natural protein carriers of the AB5 toxin family to this challenge has been restricted owing to still unresolved requirements for assembling non-native cargo into ...
Bruce R. Lichtenstein, Birte Höcker
openaire +5 more sources
Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier
Biology, 2020 The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated.
José Edwin Neciosup Quesñay +8 more
doaj +1 more source
Journal of the American Chemical Society, 2014 Acyl carrier proteins (ACPs) are universal and highly conserved domains central to both fatty acid and polyketide biosynthesis. These proteins tether reactive acyl intermediates with a swinging 4′-phosphopantetheine (Ppant) arm and interact with a suite ...
Matthew N. R. Johnson +2 more
semanticscholar +1 more source
Exploiting sulphur-carrier proteins from primary metabolism for 2-thiosugar biosynthesis
Nature, 2014 Sulphur is an essential element for life and is ubiquitous in living systems. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood.
E. Sasaki +9 more
semanticscholar +1 more source
Медицинская иммунологияThis article provides a comprehensive overview of research focusing on the role of antibodies, cytokines, complement proteins, major histocompatibility complex (MHC) molecules, and Toll-like receptors (TLRs) in the immune response and their potential as ...
S. S. Gogina, A. M. Stoinova
doaj +1 more source
Molecular Plant-Microbe Interactions, 2022 In Xanthomonas spp., the biosynthesis of the yellow pigment xanthomonadin and fatty acids originates in the type II polyketide synthase (PKS II) and fatty acid synthase (FAS) pathways, respectively. The acyl carrier protein (ACP) is the central component
Yi-Cai Chen +8 more
doaj +1 more source
A conserved motif flags Acyl Carrier Proteins for β-branching in polyketide synthesis
Nature Chemical Biology, 2013 Type I PKSs often utilise programmed β-branching, via enzymes of an “HMG-CoA synthase (HCS) cassette”, to incorporate various side chains at the second carbon from the terminal carboxylic acid of growing polyketide backbones.
A. Haines +20 more
semanticscholar +1 more source
Acyl Carrier Protein in Mycoplasmas [PDF]
Journal of Bacteriology, 1973 Acyl carrier protein (ACP) activity was determined by the malonyl-coenzyme A–CO 2 exchange reaction. It was highest in Acholeplasma laidlawii , lower in A. granularum , and lowest in A. axanthum . The sterol-requiring Mycoplasma
S, Rottem, O, Muhsam-Peled, S, Razin
openaire +2 more sources