Results 41 to 50 of about 7,114,272 (394)

Single-cell-based system to monitor carrier driven cellular auxin homeostasis [PDF]

open access: yes, 2013
Background: Abundance and distribution of the plant hormone auxin play important roles in plant development. Besides other metabolic processes, various auxin carriers control the cellular level of active auxin and, hence, are major regulators of cellular
Barbez, Elke   +7 more
core   +3 more sources

A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms

open access: yesFood Innovation and Advances, 2023
Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao   +6 more
doaj   +1 more source

New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

open access: yesAngewandte Chemie, 2016
The nonribosomal peptide synthetases (NRPSs) are one of the most promising resources for the production of new bioactive molecules. The mechanism of NRPS catalysis is based around sequential catalytic domains: these are organized into modules, where each
Tiia Kittilä   +3 more
semanticscholar   +1 more source

Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier

open access: yesBiology, 2020
The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated.
José Edwin Neciosup Quesñay   +8 more
doaj   +1 more source

Mitochondrial Protein Import [PDF]

open access: yes, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Arends   +72 more
core   +1 more source

Acid-Labile Traceless Click Linker for Protein Transduction [PDF]

open access: yes, 2012
Intracellular delivery of active proteins presents an interesting approach in research and therapy. We created a protein transduction shuttle based on a new traceless click linker that combines the advantages of click reactions with implementation of ...
Bachelder E. M.   +21 more
core   +1 more source

Probing the Phosphopantetheine Arm Conformations of Acyl Carrier Proteins Using Vibrational Spectroscopy

open access: yesJournal of the American Chemical Society, 2014
Acyl carrier proteins (ACPs) are universal and highly conserved domains central to both fatty acid and polyketide biosynthesis. These proteins tether reactive acyl intermediates with a swinging 4′-phosphopantetheine (Ppant) arm and interact with a suite ...
Matthew N. R. Johnson   +2 more
semanticscholar   +1 more source

Ligands and carriers for enhancing immune activity: Mechanisms of action and prospects for applications in medicine and biotechnology

open access: yesМедицинская иммунология
This article provides a comprehensive overview of research focusing on the role of antibodies, cytokines, complement proteins, major histocompatibility complex (MHC) molecules, and Toll-like receptors (TLRs) in the immune response and their potential as ...
S. S. Gogina, A. M. Stoinova
doaj   +1 more source

Mitochondrial precursor proteins are imported through a hydrophilic membrane environment [PDF]

open access: yes, 1987
We have analyzed how translocation intermediates of imported mitochondrial precursor proteins, which span contact sites, interact with the mitochondrial membranes.
Anderson D.   +38 more
core   +1 more source

Exploiting sulphur-carrier proteins from primary metabolism for 2-thiosugar biosynthesis

open access: yesNature, 2014
Sulphur is an essential element for life and is ubiquitous in living systems. Yet how the sulphur atom is incorporated into many sulphur-containing secondary metabolites is poorly understood.
E. Sasaki   +9 more
semanticscholar   +1 more source

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