Results 41 to 50 of about 560,339 (380)

Precursor proteins in transit through mitochondrial contact sites interact with hsp70 in the matrix [PDF]

, 1990
We previously reported that hsp70 in the mitochondrial matrix (mt-hsp70 = Ssc1p) is required for import of precursor proteins destined for the matrix or intermembrane space.
Chamberlain, Cheng, Craig, Craig, Daum, Elizabeth A. Craig, Hartl, Hartl, Hartl, Hawlitschek, Hwang, Joachim Ostermann, Kang, Klingenberg, Laemmli, Mahlke, Neupert, Nicholson, Nikolaus Pfanner, Ostermann, Pelham, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pil Jung Kang, Rassow, Rothman, Schleyer, Schwaiger, Steger, Söllner, Vestweber, Vogel, Walter Neupert, Wolfgang Voos, Yang, Zimmermann   +40 more
core   +1 more source

Mitochondrial protein import [PDF]

, 1988
The precursors of the mitochondrial proteins ADP/ATP carrier (AAC) and F1-ATPase subunit β (F1β) were accumulated at the stages of binding to receptor sites on the mitochondrial outer membrane, or in contact sites between outer and inner membranes ...
Neupert, Walter, Pfanner, Nikolaus, Söllner, Thomas   +2 more
core   +1 more source

Expression and function of Met-tRNAiMet carrier proteins in acute myeloid leukemia [PDF]

Jichu yixue yu linchuang, 2021
Objective To investigate the expression of Met-tRNAiMetcarrier proteins eIF2A, eIF2D and MCTS1 in normal hematopoietic stem cells (HSCs) and acute myeloid leukemia (AML) cells, and to study the effect of carrier proteins on the functions of AML cell ...
SU Peng-zhong, HE Jia-huan, YU Shan, WANG Xiao-shuang, YU Jia
doaj  

Counterion-release entropy governs the inhibition of serum proteins by polyelectrolyte drugs [PDF]

Biomacromolecules, 2018, 19 (2), pp 409-416, 2017
Dendritic polyelectrolytes constitute high potential drugs and carrier systems for biomedical purposes, still their biomolecular interaction modes, in particular those determining the binding affinity to proteins, have not been rationalized. We study the interaction of the drug candidate dendritic polyglycerol sulfate (dPGS) with serum proteins using ...
arxiv   +1 more source

Requirement of a Membrane Potential for the Posttranslational Transfer of Proteins into Mitochondsria [PDF]

, 1982
Posttranslational transfer of most precursor proteins into mitochondria is dependent on energization of the mitochondria. Experiments were carried out to determine whether the membrane potential or the intramitochondrial ATP is the immediate energy ...
Conboy J. G., Cote C., Daniels C. J., Data T., Date T., Enequist H. G., Graven S. N., Hallermayer G., Harmey M. A., Harmey M. A., Heldt H. W., Heytler P. G., Josefson L. G., Kekssler S. W., Korb H., Kovac L., Laemmli U. K., Lambowitz A. M., Lambowitz A. M., Maccechini M.-L., Matsuura S., Michel R., Mori M., Mori M., Nelson N., Passarella S., Pelham H. R. B., Raymond Y., Sebald W., Sebald W., Stigall D. L., Subik J., Tzagoloff A., Vignais P. V., Weiss H., Zimmermann R., Zimmermann R., Zimmermann R.   +37 more
core   +1 more source

Legionella pneumophila secretes a mitochondrial carrier protein during infection.

PLoS Pathogens, 2012
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow   +16 more
doaj   +1 more source

A review on protein based nanocarriers for polyphenols: interaction and stabilization mechanisms

Food Innovation and Advances, 2023
Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life. Interactions of a protein molecule with polyphenols are important, which change functions and physiochemical properties of the complex and ...
Yun Xiao, Talha Ahmad, Tarun Belwal, Rana Muhammad Aadil, Muhammad Siddique, Limin Pang, Yanqun Xu   +6 more
doaj   +1 more source

Mitochondrial Protein Import [PDF]

, 1987
The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Arends, Argan, Argan, Bogner, Bogner, Bradford, Böhni, Böhni, Chamberlain, Chen, Chen, Conboy, Eilers, Emr, Firgaira, Flügge, Frank, Gasser, Geller, Grossman, Gubler, Hanahan, Hansen, Harmey, Hartl, Hay, Hennig, Hennig, Horwich, Hurt, Hurt, Jaenicke, Keng, Kolanski, Maniatis, McAda, Miura, Miura, Mueckler, Nicholls, Nunberg, Ohta, Pelham, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Randall, Riezman, Roise, Rothblatt, Rothman, Schlenstedt, Schleyer, Schleyer, Schleyer, Schmidt, Schmidt, Schwaiger, Sebald, Stueber, van Loon, van Loon, Viebrock, Waters, Wiech, Wikstrom, Zimmermann, Zimmermann, Zwizinski, Zwizinski, Zwizinski   +72 more
core   +4 more sources

Transport proteins (carriers) of mitochondria [PDF]

IUBMB Life, 2008
AbstractMitochondria are subcellular structures essential to the aerobic eukaryotic cell. Their role extends much beyond their basic reactions of oxidative phosphorylation. It encompasses the steps critical for cellular metabolic pathways, for apoptosis, and for other processes such as antiviral signaling.
openaire   +3 more sources

Insights on the Quest for the Structure–Function Relationship of the Mitochondrial Pyruvate Carrier

Biology, 2020
The molecular identity of the mitochondrial pyruvate carrier (MPC) was presented in 2012, forty years after the active transport of cytosolic pyruvate into the mitochondrial matrix was first demonstrated.
José Edwin Neciosup Quesñay, Naomi L. Pollock, Raghavendra Sashi Krishna Nagampalli, Sarah C. Lee, Vijayakumar Balakrishnan, Sandra Martha Gomes Dias, Isabel Moraes, Tim R. Dafforn, Andre Luis Berteli Ambrosio   +8 more
doaj   +1 more source