Enhanced Tissue Integration During Cartilage RepairIn VitroCan Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge [PDF]
Objective: Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair.
Archer, Charles W.+7 more
core +1 more source
Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage. [PDF]
The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties ...
Szarko, M, Xia, Y
core +1 more source
Recent Progress in Cartilage Lubrication [PDF]
Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently‐lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high pressures.
Weifeng Lin, J. Klein
semanticscholar +1 more source
24R,25-Dihydroxyvitamin D3 Protects against Articular Cartilage Damage following Anterior Cruciate Ligament Transection in Male Rats [PDF]
Osteoarthritis (OA) in humans is associated with low circulating 25-hydroxyvitamin D3 [25 (OH)D3]. In vitamin D replete rats, radiolabeled 24R,25-dihydroxyvitamin D3 [24R,25 (OH)2D3] accumulates in articular cartilage following injection of [3 H]-25(OH ...
Boyan, Barbara D.+6 more
core +4 more sources
Osteoarthritis severely decreases the elasticity and hardness of knee joint cartilage: A nanoindentation study [PDF]
The nanoindentation method was applied to determine the elastic modulus and hardness of knee articular cartilage. Cartilage samples from both high weight bearing (HWB) and low weight bearing (LWB) femoral condyles were collected from patients diagnosed ...
Giersig, Michael+4 more
core +1 more source
Differential gene expression associated with postnatal equine articular cartilage maturation
Background Articular cartilage undergoes an important maturation process from neonate to adult that is reflected by alterations in matrix protein organization and increased heterogeneity of chondrocyte morphology.
Stromberg Arnold J+3 more
doaj +1 more source
Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]
Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D+2 more
core +2 more sources
Runt-related transcription factor 1 (Runx1) plays a key role in cartilage formation, but its function in articular cartilage formation is unclear. We generated non-inducible and inducible Runx1-deficient mice (Runx1 f/f Col2α1-Cre and Runx1 f/f Col2α1 ...
Yan Zhang+5 more
doaj +1 more source
Abstract Based on histological cross‐sections, the chondrocranium of the common musk turtle (Sternotherus odoratus) was reconstructed, described, and compared with other turtles. It differs from that of other turtle chondrocrania by possessing elongated, slightly dorsally orientated nasal capsules with three dorsolateral foramina, which might be ...
Luca Leicht+2 more
wiley +1 more source
Craniogenetic studies in Sus scrofa: With emphasis on the ‘orbitosphenoid’ problem
Abstract The orbitosphenoid is a skeletal element of the endocranium of extant mammals. However, it has also been described in many of their fossil ancestors. Craniogenetic studies show that it is composed of two types of bone: first, the cartilaginous ala orbitalis and parts of the trabecular plate are transformed by endochondral ossification; second,
Wolfgang Maier, Ulla Lächele, Irina Ruf
wiley +1 more source