Results 61 to 70 of about 158,746 (284)

Tensorial Electrokinetics in Articular Cartilage [PDF]

open access: yesBiophysical Journal, 2006
Electrokinetic phenomena contribute to biomechanical functions of articular cartilage and underlie promising methods for early detection of osteoarthritic lesions. Although some transport properties, such as hydraulic permeability, are known to become anisotropic with compression, the direction-dependence of cartilage electrokinetic properties remains ...
Thomas M. Quinn, Boris Reynaud
openaire   +3 more sources

Osteoarthritis severely decreases the elasticity and hardness of knee joint cartilage: A nanoindentation study [PDF]

open access: yes, 2019
The nanoindentation method was applied to determine the elastic modulus and hardness of knee articular cartilage. Cartilage samples from both high weight bearing (HWB) and low weight bearing (LWB) femoral condyles were collected from patients diagnosed ...
Giersig, Michael   +4 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Nutrition and degeneration of articular cartilage [PDF]

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, 2012
AbstractPurposeTo determine the importance of synovial fluid (SF) or subchondral bone marrow (BM) as nutrition sources in cartilage degeneration.MethodsNinety‐five‐month‐old male rabbits were randomly divided into 5 groups according to sources of nutrition: SFBM‐both; BM‐only; SF‐only; None‐SFBM; and Free plug (unrestricted). Nutrition to 4‐mm‐diameter
Yuze Wang   +5 more
openaire   +3 more sources

Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo [PDF]

open access: yes, 2013
INTRODUCTION: Signals from the epidermal growth factor receptor (EGFR) have typically been considered to provide catabolic activities in articular cartilage, and accordingly have been suggested to have a causal role in osteoarthritis progression. The aim
Caroline N Dealy   +4 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Magnetically targeted delivery through cartilage

open access: yesAIP Advances, 2018
In this study, we have invented a method of delivering drugs deep into articular cartilage with shaped dynamic magnetic fields acting on small metallic magnetic nanoparticles with polyethylene glycol coating and average diameter of 30 nm.
Sahar Jafari   +11 more
doaj   +1 more source

Cartilaginous Organoids: Advances, Applications, and Perspectives

open access: yesAdvanced NanoBiomed Research, 2023
Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu   +4 more
doaj   +1 more source

Injectable hypoxia-preconditioned cartilage progenitor cells-laden GelMA microspheres system for enhanced osteoarthritis treatment

open access: yesMaterials Today Bio, 2023
Osteoarthritis (OA) is the most common age-related degenerative joint disease mainly characterized by the destruction of articular cartilage. Owing to its native avascular property, intrinsic repair of articular cartilage is very limited.
Kai Feng   +7 more
doaj   +1 more source

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

open access: yesAdvanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula   +1 more
wiley   +1 more source

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