A scaffold-free approach to cartilage tissue generation using human embryonic stem cells
Scientific Reports, 2021 Articular cartilage functions as a shock absorber and facilitates the free movement of joints. Currently, there are no therapeutic drugs that promote the healing of damaged articular cartilage. Limitations associated with the two clinically relevant cell
Lauren A. Griffith +4 more
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A Measure of Control for Secondary Cytokine-Induced Injury of Articular Cartilage: A Computational Study [PDF]
, 2013 In previous works, the author and collaborators establish a mathematical model for injury response in articular cartilage. In this paper we use mathematical software and computational techniques, applied to an existing model to explore in more detail how
Graham, Jason M
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A homeostatic function of CXCR2 signalling in articular cartilage [PDF]
, 2014 Funding This work was funded by Arthritis Research UK (grants 17859, 17971, 19654), INNOCHEM EU FP6 (grant LSHB-CT-2005-51867), MRC (MR/K013076/1) and the William Harvey Research FoundationPeer reviewedPublisher ...
Aberdeen +17 more
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Molecular characterization of articular cartilage from young adults with femoroacetabular impingement [PDF]
, 2013 BACKGROUND: Femoroacetabular impingement is a frequent cause of hip pain and may lead to secondary osteoarthritis, yet little is known about the molecular events linking mechanical hip impingement and articular cartilage degeneration.
Clohisy, John C. +5 more
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Mesenchymal Stem Cells for Treating Articular Cartilage Defects and Osteoarthritis
Cell Transplantation, 2015 Articular cartilage damage and osteoarthritis are the most common joint diseases. Joints are prone to damage caused by sports injuries or aging, and such damage regularly progresses to more serious joint disorders, including osteoarthritis, which is a ...
Yu Wang +4 more
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Preliminary characterisation of the surface of cartilage following exposure to saturated and unsaturated synthetic lips [PDF]
, 2011 Articular cartilage is covered by a microscopic structure known as surface amorphous layer. This surface structure is often the first victim of attack during cartilage degeneration, thereby resulting in a gross impairment in cartilage function such as ...
Gudimetla, Prasad +3 more
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Nanofibrous poly(3-hydroxybutyrate)/poly(3-hydroxyoctanoate) scaffolds provide a functional microenvironment for cartilage repair [PDF]
, 2016 Articular cartilage defects, when repaired ineffectively, often lead to further deterioration of the tissue, secondary osteoarthritis and, ultimately, joint replacement.
Andriotis, Orestis G. +8 more
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Segmentation of articular cartilage and early osteoarthritis based on the fuzzy soft thresholding approach driven by modified evolutionary ABC optimization and local statistical aggregation [PDF]
, 2019 Articular cartilage assessment, with the aim of the cartilage loss identification, is a crucial task for the clinical practice of orthopedics. Conventional software (SW) instruments allow for just a visualization of the knee structure, without post ...
Augustynek, Martin +4 more
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Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation
, 2013 We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al.
Ayati, Bruce P. +5 more
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THE THERAPEUTIC TACTICS OF INTRA-ARTICULAR FRACTURES OF THE ANKLE (LITERATURE REVIEW)
Acta Biomedica Scientifica, 2013 As a result of the analysis of literature it was revealed that in case of pronation-abduction ankle injury takes place injury of the articular surfaces. The hyaline cartilage significantly suffers.
I. V. Zedgenidze, N. V. Tishkov
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