Results 31 to 40 of about 549,222 (239)

Cartilage organoids for cartilage development and cartilage-associated disease modeling

Frontiers in Cell and Developmental Biology, 2023
Cartilage organoids have emerged as powerful modelling technology for recapitulation of joint embryonic events, and cartilage regeneration, as well as pathophysiology of cartilage-associated diseases. Recent breakthroughs have uncovered “mini-joint” models comprising of multicellular components and extracellular matrices of joint cartilage for ...
Weiping Lin, Weiping Lin, Min Wang, Liangliang Xu, Micky Tortorella, Micky Tortorella, Gang Li, Gang Li, Gang Li   +8 more
openaire   +3 more sources

Deep learning-based fully automatic segmentation of wrist cartilage in MR images

, 2020
The study objective was to investigate the performance of a dedicated convolutional neural network (CNN) optimized for wrist cartilage segmentation from 2D MR images.
Andreychenko, Anna, Bendahan, David, Brui, Ekaterina, Efimtcev, Aleksandr Y., Fernandez, Remi, Fokin, Vladimir A., Levchuk, Anatoliy G., Mattei, Jean. P., Melchakova, Irina V., Ogier, Augustin C., Samsonov, Alexey A.   +10 more
core   +3 more sources

Quantitative geometric analysis of rib, costal cartilage and sternum from childhood to teenagehood [PDF]

, 2013
Better understanding of the effects of growth on children’s bones and cartilage is necessary for clinical and biomechanical purposes. The aim of this study is to define the 3D geometry of children’s rib cages: including sternum, ribs and costal cartilage.
BADINA, Alina, LAMBOT, Karene, LAPORTE, Sébastien, MITTON, David, SANDOZ, Baptiste, SKALLI, Wafa   +5 more
core   +4 more sources

NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis

Frontiers in Microbiology, 2020
Staphylococcus aureus (S. aureus) infection-induced osteomyelitis is a great challenge in clinic treatment. Identification of the essential genes and biological processes that are specifically changed in mononuclear cells at an early stage of S.
Yutian Wang, Yutian Wang, Yihuang Lin, Yihuang Lin, Caiyu Cheng, Caiyu Cheng, Pengyu Chen, Pengyu Chen, Ping Zhang, Hangtian Wu, Hangtian Wu, Kaiqun Li, Kaiqun Li, Ye Deng, Ye Deng, Jikun Qian, Jikun Qian, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +20 more
doaj   +1 more source

Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes [PDF]

European Cells & Materials, 2017
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.
Ø Arlov, E Öztürk, M Steinwachs, G Skjåk-Bræk, M Zenobi-Wong   +4 more
doaj   +1 more source

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Persistent Biomechanical Alterations After ACL Reconstruction Are Associated With Early Cartilage Matrix Changes Detected by Quantitative MR. [PDF]

, 2016
BackgroundThe effectiveness of anterior cruciate ligament (ACL) reconstruction in preventing early osteoarthritis is debated. Restoring the original biomechanics may potentially prevent degeneration, but apparent pathomechanisms have yet to be described.
Amano, Keiko, Li, Xiaojuan, Ma, C Benjamin, Pedoia, Valentina, Souza, Richard B, Su, Favian   +5 more
core   +3 more sources

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source

Antenatal Corticosteroid Therapy Attenuates Angiogenesis Through Inhibiting Osteoclastogenesis in Young Mice

Frontiers in Cell and Developmental Biology, 2020
Antenatal corticosteroid therapy (ACT) has been shown to reduce morbidity and mortality rates in preterm delivery, but the fetus is more likely to face the risk of low bone mineralization and low fetal linear growth.
Yu Chai, Yu Chai, Jianwen Su, Jianwen Su, Weisheng Hong, Weisheng Hong, Runjiu Zhu, Runjiu Zhu, Caiyu Cheng, Caiyu Cheng, Lei Wang, Lei Wang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source