Results 31 to 40 of about 502,749 (311)

Detecting new microRNAs in human osteoarthritic chondrocytes identifies miR-3085 as a human, chondrocyte-selective, microRNA [PDF]

, 2015
Objective: To use deep sequencing to identify novel microRNAs in human osteoarthritic cartilage which have a functional role in chondrocyte phenotype or function.
Aigner, Andresen Eguiluz, Barter, Benz, Bernardo, Casagrande, Chong, Culley, D.A. Young, Diaz-Prado, Dudek, G. Wheeler, Gao, Git, Goldring, Goldring, Gomez, Grgurevic, Guo, H. Pais, Himly, I.M. Clark, Ijiri, Iliopoulos, Jin, Jones, Kato, Kozomara, L.T.T. Le, Le, Liu, Loeser, Lories, M.J. Barter, Martinez-Sanchez, Miyaki, Moxon, N. Crowe, Nakamura, Nakamura, Peffers, Prufer, S.T. Donell, Scanzello, Scott, Scott, Singh, Sorefan, Steck, Sun, Swingler, T. Dalmay, T.E. Swingler, Tardif, Team, Troeberg, Winter, Xiao, Yang, Zhai   +59 more
core   +1 more source

New frontiers for cartilage repair, joint preservation and prevention

Journal of Cartilage & Joint Preservation, 2022
Damaged cartilage is seen with increasing frequency after joint trauma, alone or in combination with other joint injuries. A poor healing of injured cartilage leads to great disability and pain and could by time develop into osteoarthritis (OA).
Mats Brittberg
doaj  

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Recent progress in cartilage lubrication [PDF]

arXiv, 2023
Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently-lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high pressures. Such low friction is indeed essential for its well being.
arxiv  

Segmentation of articular cartilage and early osteoarthritis based on the fuzzy soft thresholding approach driven by modified evolutionary ABC optimization and local statistical aggregation [PDF]

, 2019
Articular cartilage assessment, with the aim of the cartilage loss identification, is a crucial task for the clinical practice of orthopedics. Conventional software (SW) instruments allow for just a visualization of the knee structure, without post ...
Augustynek, Martin, Kubíček, Jan, Oczka, David, Penhaker, Marek, Černý, Martin   +4 more
core   +1 more source

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Enhanced Tissue Integration During Cartilage RepairIn VitroCan Be Achieved by Inhibiting Chondrocyte Death at the Wound Edge [PDF]

, 2009
Objective: Experimental wounding of articular cartilage results in cell death at the lesion edge. The objective of this study was to investigate whether inhibition of this cell death results in enhanced integrative cartilage repair.
Archer, Charles W., Burdon, Drew, Duance, Victor C., Gilbert, Sophie J., Gonzalez, Lee G., Khan, Ilyas M., Singhrao, Simarjit Kaur, Thomson, Brian M.   +7 more
core   +1 more source

Osteoarthritis severely decreases the elasticity and hardness of knee joint cartilage: A nanoindentation study [PDF]

, 2019
The nanoindentation method was applied to determine the elastic modulus and hardness of knee articular cartilage. Cartilage samples from both high weight bearing (HWB) and low weight bearing (LWB) femoral condyles were collected from patients diagnosed ...
Giersig, Michael, Mieloch, Adam Aron, Richter, Magdalena, Rybka, Jakub Dalibor, Trzeciak, Tomasz   +4 more
core   +1 more source

High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer

BioTechniques, 2014
Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to-transfect cell type typically results in considerable ...
Brent E. Bobick, Peter G. Alexander, Rocky S. Tuan   +2 more
doaj   +1 more source

Scanning electrochemical microscopy as a local probe of oxygen permeability in cartilage [PDF]

, 2000
The use of scanning electrochemical microscopy, a high-resolution chemical imaging technique, to probe the distribution and mobility of solutes in articular cartilage is described.
Allhands, Anna L. Barker, Bard, Bard, Bard, Barker, Barker, Bath, Bernich, Burstein, C. Peter Winlove, Carleton, Danny O’Hare, Fischer, Fournier, Gribbon, Hansma, Horky, Hunziker, Julie V. Macpherson, Jurvelin, Knauss, Korchev, Kwak, Macpherson, Macpherson, Macpherson, Maroudas, Maroudas, Marylou Gonsalves, Matsue, Mirkin, Mow, Muehleman, Patrick R. Unwin, Potter, Roberts, Saito, Scott, Scott, Scott, Scott, Shrive, Stockwell, Torzilli, Torzilli, Unwin, Urban, Weinberg   +48 more
core   +2 more sources