Results 41 to 50 of about 715,314 (337)

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Antenatal Corticosteroid Therapy Attenuates Angiogenesis Through Inhibiting Osteoclastogenesis in Young Mice

Frontiers in Cell and Developmental Biology, 2020
Antenatal corticosteroid therapy (ACT) has been shown to reduce morbidity and mortality rates in preterm delivery, but the fetus is more likely to face the risk of low bone mineralization and low fetal linear growth.
Yu Chai, Yu Chai, Jianwen Su, Jianwen Su, Weisheng Hong, Weisheng Hong, Runjiu Zhu, Runjiu Zhu, Caiyu Cheng, Caiyu Cheng, Lei Wang, Lei Wang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

How to salvage the delivery of a wrong-sided meniscal allograft: A rare case series

Journal of Cartilage & Joint Preservation, 2021
Introduction: Although rare, tissue processing errors have occurred during meniscal transplantation. The anatomic differences between the lateral and medial menisci makes this problematic for surgeons who find themselves with an incorrectly labeled graft.
Andrew Gudeman, Iain Murray, Seth L. Sherman, Jack Farr   +3 more
doaj   +1 more source

Histological Analysis of Failed Cartilage Repair after Marrow Stimulation for the Treatment of Large Cartilage Defect in Medial Compartmental Osteoarthritis of the Knee [PDF]

, 2013
Bone marrow-stimulating techniques such as microfracture and subchondral drilling are valuable treatments for full-thickness cartilage defects. However, marrow stimulation-derived reparative tissues are not histologically well-documented in human ...
Abe, Nobuhiro, Furumatsu, Takayuki, Miyazawa, Shinichi, Ozaki, Toshifumi, Sakata, Kenichiro, Sakoma, Yoshimasa   +5 more
core   +1 more source

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source

Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes [PDF]

European Cells & Materials, 2017
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.
Ø Arlov, E Öztürk, M Steinwachs, G Skjåk-Bræk, M Zenobi-Wong   +4 more
doaj   +1 more source

High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer

BioTechniques, 2014
Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to-transfect cell type typically results in considerable ...
Brent E. Bobick, Peter G. Alexander, Rocky S. Tuan   +2 more
doaj   +1 more source

Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis [PDF]

, 2017
OBJECTIVE: The aggrecanase ADAMTS-5 and the collagenase matrix metalloproteinase 13 (MMP-13) are constitutively secreted by chondrocytes in normal cartilage, but rapidly endocytosed via the cell surface endocytic receptor low-density lipoprotein receptor-
Botkjaer, K A, Dudhia, J, Itoh, Y, Murphy, G, Nagase, H, Santamaria, S, Troeberg, L, Yamamoto, K   +7 more
core   +5 more sources

Copper-Containing Alloy as Immunoregulatory Material in Bone Regeneration via Mitochondrial Oxidative Stress

Frontiers in Bioengineering and Biotechnology, 2021
In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in ...
Daorong Xu, Daorong Xu, Jikun Qian, Jikun Qian, Xin Guan, Xin Guan, Ling Ren, Kaifan Yang, Kaifan Yang, Xuan Huang, Shuyuan Zhang, Yu Chai, Yu Chai, Xiaohu Wu, Xiaohu Wu, Hangtian Wu, Hangtian Wu, Xianrong Zhang, Xianrong Zhang, Ke Yang, Bin Yu, Bin Yu   +21 more
doaj   +1 more source

Use of autologous adipose-derived mesenchymal stem cells for creation of laryngeal cartilage [PDF]

, 2017
OBJECTIVES/HYPOTHESIS: Adipose-derived mesenchymal stem cells (ASCs) are an exciting potential cell source for tissue engineering because cells can be derived from the simple excision of autologous fat.
Brookes, Sarah, Halum, Stacey, Parker, Noah, Voytik-Harbin, Sherry, Wallace, Joseph, Zhang, Hongji, Zhang, Lujuan   +6 more
core   +1 more source