Results 41 to 50 of about 707,817 (385)

NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis

Frontiers in Microbiology, 2020
Staphylococcus aureus (S. aureus) infection-induced osteomyelitis is a great challenge in clinic treatment. Identification of the essential genes and biological processes that are specifically changed in mononuclear cells at an early stage of S.
Yutian Wang, Yutian Wang, Yihuang Lin, Yihuang Lin, Caiyu Cheng, Caiyu Cheng, Pengyu Chen, Pengyu Chen, Ping Zhang, Hangtian Wu, Hangtian Wu, Kaiqun Li, Kaiqun Li, Ye Deng, Ye Deng, Jikun Qian, Jikun Qian, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +20 more
doaj   +1 more source

Improved diagnosis of tibiofemoral cartilage defects on MRI images using deep learning

Journal of Cartilage & Joint Preservation, 2021
Introduction: MRI is the modality of choice for cartilage imaging, however, its diagnostic performance is variable. Objectives: We aimed to evaluate whether deep learning can be utilized to accurately identify cartilage defects when applied to the ...
Gergo Merkely, M.D., Alireza Borjali, Ph.D., Molly Zgoda, Evan M. Farina, M.D., Simon Görtz, M.D., Orhun Muratoglu, Ph.D., Christian Lattermann, M.D., Kartik M. Varadarajan, Ph.D.   +7 more
doaj   +1 more source

Deep learning-based fully automatic segmentation of wrist cartilage in MR images

, 2020
The study objective was to investigate the performance of a dedicated convolutional neural network (CNN) optimized for wrist cartilage segmentation from 2D MR images.
Andreychenko, Anna, Bendahan, David, Brui, Ekaterina, Efimtcev, Aleksandr Y., Fernandez, Remi, Fokin, Vladimir A., Levchuk, Anatoliy G., Mattei, Jean. P., Melchakova, Irina V., Ogier, Augustin C., Samsonov, Alexey A.   +10 more
core   +2 more sources

Early Stage Foreign Body Reaction against Biodegradable Polymer Scaffolds Affects Tissue Regeneration during the Autologous Transplantation of Tissue-Engineered Cartilage in the Canine Model

Cell Transplantation, 2012
To overcome the weak points of the present cartilage regenerative medicine, we applied a porous scaffold for the production of tissue-engineered cartilage with a greater firmness and a 3D structure.
Yukiyo Asawa, Tomoaki Sakamoto, Makoto Komura, Makoto Watanabe, Satoru Nishizawa, Yutaka Takazawa, Tsuyoshi Takato, Kazuto Hoshi M.D., Ph.D.   +7 more
doaj   +1 more source

Apolipoprotein E deficiency potentiates macrophage against Staphylococcus aureus in mice with osteomyelitis via regulating cholesterol metabolism

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionStaphylococcus aureus (S. aureus) osteomyelitis causes a variety of metabolism disorders in microenvironment and cells. Defining the changes in cholesterol metabolism and identifying key factors involved in cholesterol metabolism disorders ...
Mincheng Lu, Mincheng Lu, Ruiyi He, Ruiyi He, Chao Li, Chao Li, Zixian Liu, Zixian Liu, Yuhui Chen, Yuhui Chen, Bingsheng Yang, Bingsheng Yang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Interleukin-1β enhances cartilage-to-cartilage integration [PDF]

European Cells and Materials, 2011
The failure of cartilages to fuse, particularly in the case of articular cartilage under conditions of repair is due to morphological and structural constraints of the tissue. Factors that impede integration include, non-vascularisation, low cellularity, and proteoglycan in the surrounding extracellular matrix acting as a natural barrier to cellular ...
Charles W. Archer, S. K. Singhrao, A. P. Hollander, R. S. Conlan, Sophie Jane Gilbert, Victor Colin Duance, D. Burdon, Lewis Francis, Ilyas M. Khan, L. G. Gonzalez   +9 more
openaire   +5 more sources

Antenatal Corticosteroid Therapy Attenuates Angiogenesis Through Inhibiting Osteoclastogenesis in Young Mice

Frontiers in Cell and Developmental Biology, 2020
Antenatal corticosteroid therapy (ACT) has been shown to reduce morbidity and mortality rates in preterm delivery, but the fetus is more likely to face the risk of low bone mineralization and low fetal linear growth.
Yu Chai, Yu Chai, Jianwen Su, Jianwen Su, Weisheng Hong, Weisheng Hong, Runjiu Zhu, Runjiu Zhu, Caiyu Cheng, Caiyu Cheng, Lei Wang, Lei Wang, Xianrong Zhang, Xianrong Zhang, Bin Yu, Bin Yu   +15 more
doaj   +1 more source

Biomimetic sulphated alginate hydrogels suppress IL-1β-induced inflammatory responses in human chondrocytes [PDF]

European Cells & Materials, 2017
Loss of articular cartilage from ageing, injury or degenerative disease is commonly associated with inflammation, causing pain and accelerating degradation of the cartilage matrix.
Ø Arlov, E Öztürk, M Steinwachs, G Skjåk-Bræk, M Zenobi-Wong   +4 more
doaj   +1 more source

How to salvage the delivery of a wrong-sided meniscal allograft: A rare case series

Journal of Cartilage & Joint Preservation, 2021
Introduction: Although rare, tissue processing errors have occurred during meniscal transplantation. The anatomic differences between the lateral and medial menisci makes this problematic for surgeons who find themselves with an incorrectly labeled graft.
Andrew Gudeman, Iain Murray, Seth L. Sherman, Jack Farr   +3 more
doaj   +1 more source

In Vivo Tibial Cartilage Strains in Regions of Cartilage-to-Cartilage Contact and Cartilage-to-Meniscus Contact in Response to Walking [PDF]

The American Journal of Sports Medicine, 2017
Background:There are currently limited human in vivo data characterizing the role of the meniscus in load distribution within the tibiofemoral joint.Purpose/Hypothesis:The purpose was to compare the strains experienced in regions of articular cartilage covered by the meniscus to regions of cartilage not covered by the meniscus. It was hypothesized that
Gangadhar M. Utturkar, Pramodh K. Ganapathy, Claude T. Moorman, Betty Liu, E. Grant Sutter, Amber T. Collins, Amy L. McNulty, Nimit Lad, Charles E. Spritzer, William E. Garrett, Louis E. DeFrate   +10 more
openaire   +3 more sources