Results 51 to 60 of about 707,817 (385)

Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis

Journal of Cartilage & Joint Preservation
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear.
Yusuf Mufti, Jared P. Sachs, Andrew S. Bi, Chloe Franzia, John Ebersole, Taylor Giordano, Brian J. Cole   +6 more
doaj   +1 more source

Engineered cartilage utilizing fetal cartilage-derived progenitor cells for cartilage repair [PDF]

Scientific Reports, 2020
AbstractThe aim of this study was to develop a fetal cartilage-derived progenitor cell (FCPC) based cartilage gel through self-assembly for cartilage repair surgery, with clinically useful properties including adhesiveness, plasticity, and continued chondrogenic remodeling after transplantation.
Do Young Park, Byoung-Hyun Min, So Ra Park, Hyun Ju Oh, Minh-Dung Truong, Mijin Kim, Ja-Young Choi, In-Su Park, Byung Hyune Choi   +8 more
openaire   +2 more sources

High efficiency transfection of embryonic limb mesenchyme with plasmid DNA using square wave pulse electroporation and sucrose buffer

BioTechniques, 2014
Micromass cultures of primary embryonic limb mesenchyme are a valuable model system for studying cartilage formation in vitro. However, high efficiency introduction of plasmid DNA into this hard-to-transfect cell type typically results in considerable ...
Brent E. Bobick, Peter G. Alexander, Rocky S. Tuan   +2 more
doaj   +1 more source

Copper-Containing Alloy as Immunoregulatory Material in Bone Regeneration via Mitochondrial Oxidative Stress

Frontiers in Bioengineering and Biotechnology, 2021
In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in ...
Daorong Xu, Daorong Xu, Jikun Qian, Jikun Qian, Xin Guan, Xin Guan, Ling Ren, Kaifan Yang, Kaifan Yang, Xuan Huang, Shuyuan Zhang, Yu Chai, Yu Chai, Xiaohu Wu, Xiaohu Wu, Hangtian Wu, Hangtian Wu, Xianrong Zhang, Xianrong Zhang, Ke Yang, Bin Yu, Bin Yu   +21 more
doaj   +1 more source

Impact testing to determine the mechanical properties of articular cartilage in isolation and on bone [PDF]

, 2009
The original publication is available at www.springerlink.comNon peer ...
A. ODGAARD, A. OLOYEDE, B. M. NIGG, C. COOPER, C. T. CHEN, D. L. BUTLER, E. L. RADIN, E. L. RADIN, E. L. RADIN, F. H. DAR, G. A. ATESHIAN, G. BERGMANN, G. E. KEMPSON, J. B. FINLAY, J. DEQUEKER, J. E. JEFFREY, J. E. JEFFREY, J. M. DONOHUE, J. S. JURVELIN, K. A. ATHANASIOU, L. DAHLBERG, L. S. LOHMANDER, L. S. LOHMANDER, L. V. BURGIN, L. V. BURGIN, Leanne V. Burgin, M. FORTIN, M. K. BARKER, M. T. SERINK, R. C. HAUT, R. C. THOMPSON, R. J. LEWIS, R. M. ASPDEN, R. M. ASPDEN, R. M. ASPDEN, R. U. REPO, Richard M. Aspden, S. PARK, T. FARQUHAR, W. J. STRONGE   +39 more
core   +1 more source

Cartilage extracellular matrix as a biomaterial for cartilage regeneration [PDF]

Annals of the New York Academy of Sciences, 2016
The extracellular matrix (ECM) of various tissues possesses the model characteristics that biomaterials for tissue engineering strive to mimic; however, owing to the intricate hierarchical nature of the ECM, it has yet to be fully characterized and synthetically fabricated.
Emily C. Beck, Michael S. Detamore, Emi A. Kiyotake   +2 more
openaire   +3 more sources

Cellular senescence in aging and osteoarthritis: Implications for cartilage repair

Acta Orthopaedica, 2016
— It is well accepted that age is an important contributing factor to poor cartilage repair following injury, and to the development of osteoarthritis.
Wei Seong Toh, Mats Brittberg, Jack Farr, Casper Bindzus Foldager, Andreas H Gomoll, James Hoi Po Hui, James B Richardson, Sally Roberts, Myron Spector   +8 more
doaj   +1 more source

Persistent Biomechanical Alterations After ACL Reconstruction Are Associated With Early Cartilage Matrix Changes Detected by Quantitative MR. [PDF]

, 2016
BackgroundThe effectiveness of anterior cruciate ligament (ACL) reconstruction in preventing early osteoarthritis is debated. Restoring the original biomechanics may potentially prevent degeneration, but apparent pathomechanisms have yet to be described.
Amano, Keiko, Li, Xiaojuan, Ma, C Benjamin, Pedoia, Valentina, Souza, Richard B, Su, Favian   +5 more
core   +3 more sources

Global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis burden, 1990–2021

Arthritis Care &Research, Accepted Article.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rate for site‐specific OA across 204 countries/territories were obtained from the Global Burden of Diseases Study (GBD) 2021.
Haowei Chen, Lei Si, David J Hunter, Lei Zhang, Zhe‐Sheng Chen, Xiaomeng Wang, Vicky Duong, Zhounan Zhou, Peihua Cao, Han Cen, Su'an Tang, Tianyu Chen, Houjun Xue, Zhaohua Zhu, Changhai Ding   +14 more
wiley   +1 more source

Vitamin D Receptor Genetic Polymorphisms Associate With a Decreased Susceptibility to Extremity Osteomyelitis Partly by Inhibiting Macrophage Apoptosis Through Inhibition of Excessive ROS Production via VDR-Bmi1 Signaling

Frontiers in Physiology, 2022
Background: Previous studies had reported that vitamin D receptor (VDR) gene polymorphisms were related to the development of several inflammatory disorders. However, potential links between such variations and the risk of developing a bone infection and
Xing-Qi Zhao, Xing-Qi Zhao, Hao-Yang Wan, Hao-Yang Wan, Si-Ying He, Si-Ying He, Han-Jun Qin, Han-Jun Qin, Bin Yu, Bin Yu, Nan Jiang, Nan Jiang   +11 more
doaj   +1 more source