MiR-335-5p Escaped from CircKIAA0586 Adsorption Contributes to Mechanical Overloading-Induced Cartilage Degeneration by Targeting Lymphoid-Specific Helicase. [PDF]
Research (Wash D C)Xie H +14 more
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Electroacupuncture Inhibits Cartilage Degeneration in a Rat Knee Osteoarthritis (KOA) Model by Suppressing ADAMTS5 Expression. [PDF]
CureusChuluunbat O +5 more
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Mean Cartilage Attenuation Measured <i>In Situ</i> in an Osteoarthritis Mouse Model Using Contrast-Enhanced Micro-Computed Tomography is Indicative of Cartilage Degeneration. [PDF]
CartilageSchadow JE +3 more
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Cartilage degeneration in different human joints [PDF]
Osteoarthritis and Cartilage, 2005 Variations among joints in the initiation and progression of degeneration may be explained, in part, by metabolic, biochemical and biomechanical differences. Compared to the cartilage in the knee joint, ankle cartilage has a higher content of proteoglycans and water, as well as an increased rate of proteoglycan turnover and synthesis, all of which are ...
Kuettner, K.E., Cole, A.A.
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A Molecular Cascade Underlying Articular Cartilage Degeneration
Current Drug Targets, 2020Preserving of articular cartilage is an effective way to protect synovial joints from becoming osteoarthritic (OA) joints. Understanding of the molecular basis of articular cartilage degeneration will provide valuable information in the effort to develop cartilage preserving drugs. There are currently no disease-modifying OA drugs (DMOADs) available to
Lin Xu, Yefu Li
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Articular Cartilage Aging and Degeneration
Sports Medicine and Arthroscopy Review, 1996Summary The remarkable ability of articular cartilage to provide a low-friction gliding surface and to simultaneously distribute loads across synovial joints makes possible the rapid, smooth, painless movements necessary for participation in sports.
James A. Martin, Joseph A. Buckwalter
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Osteoarthritis: More than Cartilage Degeneration
Clinical Reviews in Bone and Mineral Metabolism, 2017Osteoarthritis (OA) is nowadays considered as a global disease of the joint in which all articular structures are involved. Although articular cartilage is the primary target of the disease, both subchondral bone (SB) and synovium are structures that actively participate at the onset and in the progression of the disease. The relationship between these
Santos Castañeda, Esther F. Vicente
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Restoration of Injured or Degenerated Articular Cartilage
Journal of the American Academy of Orthopaedic Surgeons, 1994Intra-articular fractures, ligamentous and meniscal injuries, and articular cartilage breakdown are major causes of degenerative joint disease. Lesions on the articular surface seem to have a limited capacity for repair and often progress inexorably toward osteoarthritis. Recent studies on joint immobilization and cartilage atrophy, however, have shown
, Buckwalter, , Mow, , Ratcliffe
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Mid-infrared Spectroscopic Assessment of Cartilage Degeneration
Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP), 2019We introduce classification models based on partial least squares discriminant-analysis (PLS-DA) for estimating cartilage integrity (assessed by OARSI grade) based on mid-infrared spectra of cartilage matrix. The best model achieved accuracy of 84%.
Shaikh, Rubina +10 more
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