Results 121 to 130 of about 108,199 (280)
Short interfering RNA (siRNA)-Based Therapeutics for Cartilage Diseases. [PDF]
Regen Eng Transl Med, 2020 Zhou L, Rubin LE, Liu C, Chen Y.
europepmc +1 more source
Patient-Reported Outcome Measure for Cartiva® Synthetic Cartilage Replacement in Advanced Degenerative Disease of the Hallux Metatarsophalangeal Joint - A Single Surgeon Series [PDF]
, 2022 Rutnagur Joshua D
openalex +1 more source
Advanced Science, EarlyView.Glycosylation, specifically hypersialylation, is identified as a critical factor in human intervertebral disc (IVD) degeneration—a major cause of low back pain. This study demonstrates that inhibiting sialylation reduces inflammation and oxidative stress in IVD tissues, suggesting new therapeutic possibilities.
Kieran Joyce +8 more
wiley +1 more source
Frontiers in PharmacologyCartilage, a type of connective tissue, plays a crucial role in supporting and cushioning the body, and damages or diseases affecting cartilage may result in pain and impaired joint function.
Meng-Xuan Yao +21 more
doaj +1 more source
Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation
Advanced Science, EarlyView.FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin +14 more
wiley +1 more source
Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng +15 more
wiley +1 more source
New Issues in the Management of Osteoporosis
Journal of Osteoporosis, 2011 Joonas Sirola +3 more
doaj +1 more source
A Review on Biodegradable Materials of Sustainable Soft Robotics and Electronics
Advanced Science, EarlyView.Biodegradable materials are gaining increasing attention in soft robotics and electronics due to their environmental friendliness, showing great potential for sustainability. In this review, the classification of biodegradable materials, their applications in the field of soft robotics and electronics, as well as the challenges and future prospects ...
Yizhu Xie +8 more
wiley +1 more source
Corrigendum to “New Issues in the Management of Osteoporosis”
Journal of Osteoporosis, 2017 Joonas Sirola +3 more
doaj +1 more source