Results 81 to 90 of about 9,103,182 (195)
Stem cell research & therapeutics, 2017 Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of genetic information have been implicated in many diseases and are known to participate in many ...
Yafei Wang +10 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Osteoarthritis (OA) is one of the most common refractory degenerative articular cartilage diseases. Human amniotic mesenchymal cells (hAMSCs) have emerged as a promising stem cell source for cartilage repair, and hyaluronic acid (HA) has proven to be a ...
Ai-Tong Wang +7 more
semanticscholar +1 more source
Molecular and Cellular Mechanisms of Bone and Cartilage Diseases
Biomedicines, 2023 Bones and cartilage, the two most important parts of the musculoskeletal system, provide mobility and maintain the body’s posture [...]
openaire +3 more sources
Stem Cells Translational Medicine, 2016 Articular cartilage is not a physiologically self‐renewing tissue. Injury of cartilage often progresses from the articular surface to the subchondral bone, leading to pathogenesis of tissue degenerative diseases, such as osteoarthritis.
Yangzi Jiang +10 more
doaj +1 more source
Detection of Proteoglycan Loss from Articular Cartilage using Brillouin Microscopy, with Applications to Osteoarthritis [PDF]
arXiv, 2018 The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start with depletion of proteoglycan(PG), leading to an increase in tissue hydration and permeability.
arxiv
Impact-Induced Cartilage Damage Assessed using Polarisation-Sensitive Optical Coherence Tomography [PDF]
arXiv, 2020 Significance: Non-invasive determination of structural changes in articular cartilage immediately after impact and rehydration provides insight into the response and recovery of the soft tissue, as well as provides a potential methodology for clinicians to quantify early degenerative changes. Approach: A custom-designed impact testing rig was used to
arxiv
Osteoarthritis and Cartilage, 2002 OBJECTIVE To review the basic scientific status of repair in articular cartilage tissue and to assess the efficiency of current clinical therapies instigated for the treatment of structural lesions generated therein as a result of trauma or during the ...
E. Hunziker
semanticscholar +1 more source
Chondrocyte Heterogeneity; It Is the Time to Update the Understanding of Cartilage Histology [PDF]
SVU-International Journal of Veterinary Sciences (2018), 2018 Chondrocytes were described as one cell populations in most cartilage literature. Two different chondrocyte populations; dark and light, were described in the articular cartilage and a third population, adipochondrocytes, was described in the elastic cartilage.
arxiv
Fiber Reinforced Cartilage ECM Functionalized Bioinks for Functional Cartilage Tissue Engineering
Advanced Healthcare Materials, 2019 Focal articular cartilage (AC) defects, if left untreated, can lead to debilitating diseases such as osteoarthritis. While several tissue engineering strategies have been developed to promote cartilage regeneration, it is still challenging to generate ...
S. Rathan +5 more
semanticscholar +1 more source
Scientific Reports, 2016 Circular RNAs (circRNAs) are involved in the development of various diseases, but there is little knowledge of circRNAs in osteoarthritis (OA). The aim of study was to identify circRNA expression in articular cartilage and to explore the function of ...
Qiang Liu +6 more
semanticscholar +1 more source