Results 11 to 20 of about 76,092 (265)

Cell therapy for cartilage repair [PDF]

Emerging Topics in Life Sciences, 2021
Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of tissues and organs, offers great hope for the future of medicine. Cell therapy for treating defects in articular cartilage has been an exemplar of translating this technology to the clinic, but it is not without its challenges. These include applying regulations,
Charlotte H. Hulme, Jade Perry, Helen S. McCarthy, Karina T. Wright, Martyn Snow, Claire Mennan, Sally Roberts   +6 more
openaire   +3 more sources

ARTICULAR CARTILAGE–TO REPAIR OR NOT TO REPAIR [PDF]

The Journal of Bone and Joint Surgery. British volume, 2000
V. Bobic, MD, Consultant Orthopaedic Knee SurgeonRoyal Liverpool University Hospitals, Prescot Street, Liverpool L7 8XP,UK.J. Noble, ChM, FRCS, FRCS E, Consultant Orthopaedic SurgeonHope Hospital, Stott Lane, Salford M6 8HD, UK.©2000 British Editorial Society of Bone and Joint Surgery0301-620X/00/20707 $2 ...
V, Bobic, J, Noble
openaire   +2 more sources

Patellofemoral Cartilage Repair [PDF]

Current Reviews in Musculoskeletal Medicine, 2018
This review provides an overview of well-established and newly developed cartilage repair techniques for cartilage defects in the patellofemoral joint (PFJ). An algorithm will be presented for approaching cartilage defects considering the distinct anatomy of both the patellar and trochlear articular surfaces.Recent studies on cartilage repair in the ...
Mestriner, Alexandre Barbieri, Ackermann, Jakob, Gomoll, Andreas H.   +2 more
openaire   +4 more sources

Signaling Pathways in Cartilage Repair [PDF]

International Journal of Molecular Sciences, 2014
In adult healthy cartilage, chondrocytes are in a quiescent phase characterized by a fine balance between anabolic and catabolic activities. In ageing, degenerative joint diseases and traumatic injuries of cartilage, a loss of homeostatic conditions and an up-regulation of catabolic pathways occur.
MARIANI, ERMINIA, Pulsatelli, Lia, Facchini, Andrea   +2 more
openaire   +2 more sources

Biological Knee Reconstruction With Concomitant Autologous Chondrocyte Implantation and Meniscal Allograft Transplantation

Orthopaedic Journal of Sports Medicine, 2016
Background: Treating articular cartilage defects and meniscal deficiency is challenging. Although some short- to mid-term follow-up studies report good clinical outcomes after concurrent autologous chondrocyte implantation (ACI) and meniscal allograft ...
Takahiro Ogura MD, Tim Bryant BSN, RN, Tom Minas MD, MS   +2 more
doaj   +1 more source

Autologous Chondrocyte Implantation “Segmental-Sandwich” Technique for Deep Osteochondral Defects in the Knee: Clinical Outcomes and Correlation With Magnetic Resonance Imaging Findings

Orthopaedic Journal of Sports Medicine, 2019
Background: Symptomatic osteochondral defects are difficult to manage, especially in patients with deep (>8-10 mm) empty defects. The restoration of articular congruence is crucial to avoid the progression to osteoarthritis (OA). Purpose: To describe the
Takahiro Ogura MD, Gergo Merkely MD, Tim Bryant BSN, RN, Carl S. Winalski MD, Tom Minas MD, MS   +4 more
doaj   +1 more source

Intermediate- to Long-Term Results of Combined Anterior Cruciate Ligament Reconstruction and Autologous Chondrocyte Implantation

Orthopaedic Journal of Sports Medicine, 2017
Background: Cartilage injury associated with anterior cruciate ligament (ACL) ruptures is common; however, relatively few reports exist on concurrent cartilage repair with ACL reconstruction.
Andrew N. Pike MD, Tim Bryant RN, Takahiro Ogura MD, Tom Minas MD   +3 more
doaj   +1 more source

Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage. [PDF]

PLoS ONE, 2010
BackgroundArticular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue.
Rebecca Williams, Ilyas M Khan, Kirsty Richardson, Larissa Nelson, Helen E McCarthy, Talal Analbelsi, Sim K Singhrao, Gary P Dowthwaite, Rhiannon E Jones, Duncan M Baird, Holly Lewis, Selwyn Roberts, Hannah M Shaw, Jayesh Dudhia, John Fairclough, Timothy Briggs, Charles W Archer   +16 more
doaj   +1 more source

A New Technique for Distalization of the Tibial Tubercle That Allows Preservation of the Proximal Buttress

Orthopaedic Journal of Sports Medicine, 2018
Background: Tibial tubercle osteotomy (TTO) is a treatment option for patients with patellofemoral instability and chondrosis. Occasionally, these patients also present with patella alta, and distalization of the tibial tubercle is desirable. Free distal
Luiz Felipe Ambra MD, PhD, Amy Phan BS, Andreas H. Gomoll MD   +2 more
doaj   +1 more source

A Worldwide Bibliometric and Visualized Analysis in Publications of Research About Hydrogel in Cartilage Repair

Frontiers in Materials, 2022
Background: Cartilage defect is a common joint disease. Hydrogels are widely used in the area of cartilage tissue engineering because of their ability to repair the defect cartilage.
Jieyu Lai, Jieyu Lai, Dengjie Yu, Dengjie Yu, Changkai Ni, Aohan Zhang, Wenfeng Xiao, Wenfeng Xiao, Yusheng Li, Yusheng Li   +9 more
doaj   +1 more source