Results 21 to 30 of about 148,666 (361)

The role of changes in extracellular matrix of cartilage in the presence of inflammation on the pathology of osteoarthritis. [PDF]

, 2013
Osteoarthritis (OA) is a degenerative disease that affects various tissues surrounding joints such as articular cartilage, subchondral bone, synovial membrane, and ligaments.
Maldonado, Maricela, Nam, Jin
core   +3 more sources

Biological Knee Reconstruction With Concomitant Autologous Chondrocyte Implantation and Meniscal Allograft Transplantation

Orthopaedic Journal of Sports Medicine, 2016
Background: Treating articular cartilage defects and meniscal deficiency is challenging. Although some short- to mid-term follow-up studies report good clinical outcomes after concurrent autologous chondrocyte implantation (ACI) and meniscal allograft ...
Takahiro Ogura MD, Tim Bryant BSN, RN, Tom Minas MD, MS   +2 more
doaj   +1 more source

Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]

, 2018
Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D, Matava, Matthew J, Schafer, Kevin A   +2 more
core   +2 more sources

Autologous Chondrocyte Implantation “Segmental-Sandwich” Technique for Deep Osteochondral Defects in the Knee: Clinical Outcomes and Correlation With Magnetic Resonance Imaging Findings

Orthopaedic Journal of Sports Medicine, 2019
Background: Symptomatic osteochondral defects are difficult to manage, especially in patients with deep (>8-10 mm) empty defects. The restoration of articular congruence is crucial to avoid the progression to osteoarthritis (OA). Purpose: To describe the
Takahiro Ogura MD, Gergo Merkely MD, Tim Bryant BSN, RN, Carl S. Winalski MD, Tom Minas MD, MS   +4 more
doaj   +1 more source

Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage. [PDF]

PLoS ONE, 2010
BackgroundArticular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue.
Rebecca Williams, Ilyas M Khan, Kirsty Richardson, Larissa Nelson, Helen E McCarthy, Talal Analbelsi, Sim K Singhrao, Gary P Dowthwaite, Rhiannon E Jones, Duncan M Baird, Holly Lewis, Selwyn Roberts, Hannah M Shaw, Jayesh Dudhia, John Fairclough, Timothy Briggs, Charles W Archer   +16 more
doaj   +1 more source

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada, Barbero, Andrea, Candrian, Christian, Gianni-Barrera, Roberto, Jaquiery, Claude, Juelke, Henriette, Mainil-Varlet, Pierre, Martin, Ivan, Miot, Sylvie, Pelttari, Karoliina   +9 more
core   +1 more source

Intermediate- to Long-Term Results of Combined Anterior Cruciate Ligament Reconstruction and Autologous Chondrocyte Implantation

Orthopaedic Journal of Sports Medicine, 2017
Background: Cartilage injury associated with anterior cruciate ligament (ACL) ruptures is common; however, relatively few reports exist on concurrent cartilage repair with ACL reconstruction.
Andrew N. Pike MD, Tim Bryant RN, Takahiro Ogura MD, Tom Minas MD   +3 more
doaj   +1 more source

Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair [PDF]

, 2010
[Abstract] The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in vivo.
Blanco García, Francisco J, De-Toro, Javier, Díaz-Prado, Silvia, Fuentes Boquete, Isaac Manuel, Hermida Gómez, Tamara, Muiños-López, Emma, Rendal Vázquez, María Esther, Rodríguez-Cabarcos, Margarita   +7 more
core   +2 more sources

Hybrid bioprinting of chondrogenically induced human mesenchymal stem cell spheroids [PDF]

, 2020
To date, the treatment of articular cartilage lesions remains challenging. A promising strategy for the development of new regenerative therapies is hybrid bioprinting, combining the principles of developmental biology, biomaterial science, and 3D ...
Asadian, Mahtab, De Geyter, Nathalie, De Moor, Lise, Declercq, Heidi, Dubruel, Peter, Fernandez, Sélina, Tytgat, Liesbeth, Van Vlierberghe, Sandra, Vercruysse, Chris   +8 more
core   +2 more sources

A New Technique for Distalization of the Tibial Tubercle That Allows Preservation of the Proximal Buttress

Orthopaedic Journal of Sports Medicine, 2018
Background: Tibial tubercle osteotomy (TTO) is a treatment option for patients with patellofemoral instability and chondrosis. Occasionally, these patients also present with patella alta, and distalization of the tibial tubercle is desirable. Free distal
Luiz Felipe Ambra MD, PhD, Amy Phan BS, Andreas H. Gomoll MD   +2 more
doaj   +1 more source