Results 21 to 30 of about 75,319 (266)
A primer in cartilage repair [PDF]
The Journal of Bone and Joint Surgery. British volume, 2012 Hyaline articular cartilage has been known to be a troublesome tissue to repair once damaged. Since the introduction of autologous chondrocyte implantation (ACI) in 1994, a renewed interest in the field of cartilage repair with new repair techniques and the hope for products that are regenerative have blossomed.
openaire +2 more sources
Preclinical Studies for Cartilage Repair [PDF]
CARTILAGE, 2011 Investigational devices for articular cartilage repair or replacement are considered to be significant risk devices by regulatory bodies. Therefore animal models are needed to provide proof of efficacy and safety prior to clinical testing. The financial commitment and regulatory steps needed to bring a new technology to clinical use can be major ...
Hurtig, Mark B. +9 more
openaire +2 more sources
Challenging for cartilage repair [PDF]
BMC Sports Science, Medicine and Rehabilitation, 2009 Editorial When we look back on the past 15-year history of cartilage repair, it is clear that remarkable progress has been made in this area. There is no doubt that a lot of studies have been carried out on cartilage repair and chondrocytes since Brittebergs' report on ACI in 1994 [1].
openaire +3 more sources
Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model. [PDF]
PLoS ONE, 2016 Mesenchymal stem cells (MSCs) are known to have therapeutic potential for cartilage repair. However, the optimal concentration of MSCs for cartilage repair remains unclear.
Yong-Beom Park +6 more
doaj +1 more source
Cartilage repair in the degenerative ageing knee: A narrative review and analysis
Acta Orthopaedica, 2016 Background and purpose — Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis.
Mats Brittberg +5 more
doaj +1 more source
Cartilaginous Organoids: Advances, Applications, and Perspectives
Advanced NanoBiomed Research, 2023 Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source
Cellular senescence in aging and osteoarthritis: Implications for cartilage repair
Acta Orthopaedica, 2016 — It is well accepted that age is an important contributing factor to poor cartilage repair following injury, and to the development of osteoarthritis.
Wei Seong Toh +8 more
doaj +1 more source
Expression and function of cartilage-derived pluripotent cells in joint development and repair
Stem Cell Research & Therapy, 2020 Cartilage-derived pluripotent cells reside in hyaline cartilage and fibrocartilage. These cells have the potential for multidirectional differentiation; can undergo adipogenesis, osteogenesis, and chondrogenesis; and have been classified as mesenchymal ...
Zhou Jiang +3 more
doaj +1 more source
Frontiers in Materials, 2022 Background: Cartilage defect is a common joint disease. Hydrogels are widely used in the area of cartilage tissue engineering because of their ability to repair the defect cartilage.
Jieyu Lai +9 more
doaj +1 more source
Advances and Prospects in Stem Cells for Cartilage Regeneration
Stem Cells International, 2017 The histological features of cartilage call attention to the fact that cartilage has a little capacity to repair itself owing to the lack of a blood supply, nerves, or lymphangion.
Mingjie Wang +16 more
doaj +1 more source