PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]
, 2019 Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin +3 more
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Meniscus-derived matrix scafolds promote the integrative repair of meniscal defects [PDF]
, 2019 Meniscal tears have a poor healing capacity, and damage to the meniscus is associated with significant pain, disability, and progressive degenerative changes in the knee joint that lead to osteoarthritis.
DeFrate, Louis E. +9 more
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Challenging for cartilage repair [PDF]
BMC Sports Science, Medicine and Rehabilitation, 2009 Editorial When we look back on the past 15-year history of cartilage repair, it is clear that remarkable progress has been made in this area. There is no doubt that a lot of studies have been carried out on cartilage repair and chondrocytes since Brittebergs' report on ACI in 1994 [1].
openaire +3 more sources
Cartilaginous Organoids: Advances, Applications, and Perspectives
Advanced NanoBiomed Research, 2023 Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source
Frontiers in Materials, 2022 Background: Cartilage defect is a common joint disease. Hydrogels are widely used in the area of cartilage tissue engineering because of their ability to repair the defect cartilage.
Jieyu Lai +9 more
doaj +1 more source
Exosomes in cartilage microenvironment regulation and cartilage repair. [PDF]
Front Cell Dev BiolOsteoarthritis (OA) is a debilitating disease that predominantly impacts the hip, hand, and knee joints. Its pathology is defined by the progressive degradation of articular cartilage, formation of bone spurs, and synovial inflammation, resulting in pain, joint function limitations, and substantial societal and familial burdens.
Longfei H +9 more
europepmc +4 more sources
Adipose, Bone Marrow and Synovial Joint-Derived Mesenchymal Stem Cells for Cartilage Repair [PDF]
, 2016 Current cell-based repair strategies have proven unsuccessful for treating cartilage defects and osteoarthritic lesions, consequently advances in innovative therapeutics are required and mesenchymal stem cell-based (MSC) therapies are an expanding area ...
Ali Mobasheri +8 more
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Cartilage repair in the degenerative ageing knee: A narrative review and analysis
Acta Orthopaedica, 2016 Background and purpose — Cartilage damage can develop due to trauma, resulting in focal chondral or osteochondral defects, or as more diffuse loss of cartilage in a generalized organ disease such as osteoarthritis.
Mats Brittberg +5 more
doaj +1 more source
Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model. [PDF]
PLoS ONE, 2016 Mesenchymal stem cells (MSCs) are known to have therapeutic potential for cartilage repair. However, the optimal concentration of MSCs for cartilage repair remains unclear.
Yong-Beom Park +6 more
doaj +1 more source
Accelerated return to sport after osteochondral autograft plug transfer [PDF]
, 2017 Background:Previous studies have reported varying return-to-sport protocols after knee cartilage restoration procedures.Purpose:To (1) evaluate the time for return to sport in athletes with an isolated chondral injury who underwent an accelerated return ...
Brockmeier, Stephen F +6 more
core +2 more sources