Results 201 to 210 of about 147,512 (341)

Editorial Commentary: Biological Cartilage Repair Technique—An “Effective, Accessible, and Safe” Surgical Solution for an Old Difficult Biological Problem [PDF]

, 2020
Alberto Gobbi, Ignácio Dallo, Vetri Kumar   +2 more
openalex   +1 more source

Catalyst‐Free Collagen Filament Crosslinking for Engineering Anisotropic and Mechanically Robust Tissue Scaffolds

Advanced Science, EarlyView.
A bioorthogonal rhodamine/PEG crosslinking strategy is introduced to engineer dense collagen hydrogels with high mechanical resilience and cytocompatibility. Integration with wet‐spinning enables the fabrication of uniaxially aligned, cell‐laden collagen filaments that activate mechanotransductive signaling and support functional muscle regeneration in
JuYeon Kim, Hanjun Hwangbo, ByungJoon Choi, Dogeon Yoon, GeunHyung Kim   +4 more
wiley   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Bridging the Gap: Do Patient-Reported Outcome Measures Reflect Objective Knee Function After Cartilage Repair? [PDF]

J Clin Med
Heinz T, Wegerich N, Frischholz S, Stratos I, Horas K, Reppenhagen S, Rudert M, Weißenberger M.   +7 more
europepmc   +1 more source

Inflammatory Responsive Hydrogels Incorporated with Bevacizumab-Loaded Infinite Coordination Nanopolymers for Accelerating Cartilage Repair

Hai‐Ning Chen, Tao Xin, Jinbo Liu, Qian Kong, Li Wang, Yiwen Zhao, Chao Jiang, Yu Song, Xu Xu, Jinjian Zhu, Yiyang Wang, F. Du, Baoding Chen, Jun Wu   +13 more
openalex   +1 more source

Articular cartilage repair and transplantation [PDF]

Arthritis & Rheumatism, 1998
J A, Buckwalter, H J, Mankin
openaire   +2 more sources

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Shocking Results of Platelet-Rich Plasma Administration Concurrent With Autologous Chondrocyte Implantation Negatively Impacting Cartilage Repair: Response. [PDF]

Orthop J Sports Med
Kato Y, Yanada S, Morikawa H.
europepmc   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Preserving Hip Stability Yields Better Cartilage Repair With Microfracture Treatment: A Rabbit Study. [PDF]

Arthrosc Sports Med Rehabil
Hajiyev E, Aydin O, Aydemir S, Yilmaz PA, Erbil G, Arslan AK, Duymaz B, Hapa O.   +7 more
europepmc   +1 more source