Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage. [PDF]
PLoS ONE, 2010 BackgroundArticular cartilage displays a poor repair capacity. The aim of cell-based therapies for cartilage defects is to repair damaged joint surfaces with a functional replacement tissue.
Rebecca Williams +16 more
doaj +1 more source
Treatment of failed articular cartilage reconstructive procedures of the knee: A systematic review [PDF]
, 2018 Background: Symptomatic articular cartilage lesions of the knee are common and are being treated surgically with increasing frequency. While many studies have reported outcomes following a variety of cartilage restoration procedures, few have ...
Lamplot, Joseph D +2 more
core +2 more sources
Characterization of the cells in repair tissue following autologous chondrocyte implantation in mankind: a novel report of two cases [PDF]
, 2013 AIM: Autologous chondrocyte implantation (ACI) is used worldwide for the treatment of cartilage defects. This study has aimed to assess for the first time the cells that are contained within human ACI repair tissues several years post-treatment.
Banerjee, R +5 more
core +2 more sources
Effect of Transplanting Various Concentrations of a Composite of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Hyaluronic Acid Hydrogel on Articular Cartilage Repair in a Rabbit Model. [PDF]
PLoS ONE, 2016 Mesenchymal stem cells (MSCs) are known to have therapeutic potential for cartilage repair. However, the optimal concentration of MSCs for cartilage repair remains unclear.
Yong-Beom Park +6 more
doaj +1 more source
In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]
, 2010 We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Acharya, Chitrangada +9 more
core +1 more source
Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair [PDF]
, 2010 [Abstract] The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in vivo.
Blanco García, Francisco J +7 more
core +2 more sources
Frontiers in Materials, 2022 Background: Cartilage defect is a common joint disease. Hydrogels are widely used in the area of cartilage tissue engineering because of their ability to repair the defect cartilage.
Jieyu Lai +9 more
doaj +1 more source
PRP and BMAC for Musculoskeletal Conditions via Biomaterial Carriers. [PDF]
, 2019 Platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) are orthobiologic therapies considered as an alternative to the current therapies for muscle, bone and cartilage. Different formulations of biomaterials have been used as carriers for
Shams, Shahin +3 more
core +1 more source
Bone marrow cells immunomagnetically selected for CD271+ antigen promote in vitro the repair of articular cartilage defects [PDF]
, 2011 [Abstract] Objective: The purposes of this project were to quantify the cells expressing the mesenchymal stem cell (MSC) marker CD271 in synovial membranes from human osteoarthritic (OA) and healthy joints, and to determine if those CD271 cells were ...
Blanco García, Francisco J +6 more
core +2 more sources
Cartilaginous Organoids: Advances, Applications, and Perspectives
Advanced NanoBiomed Research, 2023 Cartilage is a nonvascular and non‐neural, mesoderm‐derived tissue. Cartilage repair, especially articular cartilage repair and reconstruction, has always been a difficult problem in bone tissue engineering.
Yuhao Yu +4 more
doaj +1 more source