Results 51 to 60 of about 136,745 (341)

Animal models of cartilage repair

Bone & Joint Research, 2014
Cartilage repair in terms of replacement, or regeneration of damaged or diseased articular cartilage with functional tissue, is the ‘holy grail’ of joint surgery. A wide spectrum of strategies for cartilage repair currently exists and several of these techniques have been reported to be associated with successful clinical outcomes for appropriately ...
Aaron M. Stoker, Seth L. Sherman, James P. Stannard, James L. Cook, Cristi R. Cook, Ferris M. Pfeiffer, Keiichi Kuroki, Clark T. Hung   +7 more
openaire   +3 more sources

Accelerated return to sport after osteochondral autograft plug transfer [PDF]

, 2017
Background:Previous studies have reported varying return-to-sport protocols after knee cartilage restoration procedures.Purpose:To (1) evaluate the time for return to sport in athletes with an isolated chondral injury who underwent an accelerated return ...
Brockmeier, Stephen F, Cosgrove, Chris T, Diduch, David R, Gilmore, C. Jan, Lyons, Matthew L, Miller, Mark D, Werner, Brian C   +6 more
core   +2 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Quality Evaluation of Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair

Stem Cells International, 2017
Quality evaluation of mesenchymal stem cells (MSCs) based on efficacy would be helpful for their clinical application. In this study, we aimed to find the factors of human bone marrow MSCs relating to cartilage repair.
Katsunori Shiraishi, Naosuke Kamei, Shunsuke Takeuchi, Shinobu Yanada, Hisashi Mera, Shigeyuki Wakitani, Nobuo Adachi, Mitsuo Ochi   +7 more
doaj   +1 more source

Differential cartilaginous tissue formation by human synovial membrane, fat pad, meniscus cells and articular chondrocytes [PDF]

, 2007
Objective: To identify an appropriate cell source for the generation of meniscus substitutes, among those which would be available by arthroscopy of injured knee joints.
A. Adesida, A. Marsano, Adams, Ahmed, Al-Taher, AufderHeide, Barbero, Barbero, Burr, C. Chiari-Grisar, Chen, Cox, D.M. Salter, De Bari, De Bari, Dell'Accio, Demarteau, Dickinson, E. Kon, E. Tognana, Fithian, Grigolo, Gronthos, Hidaka, Higuchi, Hollander, Hunziker, I. Martin, Ibarra, Ibarra, Jakob, Jakob, Kambic, Levy, Livak, M. Jakob, Martin, Martinek, Melrose, Mikic, Miyamoto, Mochizuki, Moretti, Nakata, Ochi, Pangborn, Park, Peretti, Peretti, Peterson, Port, Reinholz, Rijk, Rijk, Roberts, S. Nehrer, S.J. Millward-Sadler, Sakaguchi, Sweigart, T. Hardingham, Tay, Valiyaveettil, Verdonk, Walsh, Weinand, Wickham, Yaeger, Yoo, Zellner   +68 more
core   +1 more source

Patient Perceptions of Medication Therapy for Prevention of Posttraumatic Osteoarthritis Following Anterior Cruciate Ligament Injury: A Qualitative Content Analysis

Arthritis Care &Research, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell, Donald P. Mitchener, Kelly C. Frier, Morgan H. Jones, Elena Losina, Nick Bansback, Liana Fraenkel, Jason S. Kim, Jeffrey N. Katz, Faith Selzer, Adam Easterbrook   +10 more
wiley   +1 more source

Advances in articular cartilage repair

Injury, 2005
Many joint and systemic disorders may lead to cartilage defects. Partial thickness defects of the articular cartilage do not have healing potential. When the lesion reaches the subchondral bone, spontaneous healing may be observed, but consists of fibrocartilaginous tissue.
Beris, A. E., Lykissas, M. G., Papageorgiou, C. D., Georgoulis, A. D.   +3 more
openaire   +4 more sources

Visual histological grading system for the evaluation of in vitro-generated neocartilage [PDF]

, 2006
Here we present the development of a visual evaluation system for routine assessment of in vitro-engineered cartilaginous tissue. Neocartilage was produced by culturing human articular chondrocytes in pellet culture systems or in a scaffold-free ...
Barbero, Andrea, Fitzsimmons, James S., Grogan, Shawn Patrick, Mainil-Varlet, Pierre, Martin, Ivan, O`Driscoll, Shawn, Rieser, Franz, Winkelmann, Verena   +7 more
core   +1 more source

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

MACI Sandwich Technique With Autologous Bone Graft

Video Journal of Sports Medicine
Background: Osteochondral lesions of the knee are difficult to manage. Such lesions can be effectively treated with the matrix-induced autologous chondrocyte implantation (MACI) “sandwich” technique using autologous chondrocytes on porcine collagen ...
Tom Minas MD, MS
doaj   +1 more source