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Tissue engineering of cartilage

Clinics in Plastic Surgery, 2003
The primary goal of engineering cartilage as a therapeutic approach is to restore the physiological conditions of an affected or defective tissue in the body. Cartilage tissue is distributed widely in the human body and possesses an organization related to the specific demand of a particular anatomical region.
Mark A, Randolph   +2 more
openaire   +4 more sources

Cartilage Tissue Engineering

2011
Cartilage tissue engineering is the art aimed at repairing defects in the articular cartilage which covers the bony ends in the joints. Since its introduction in the early 1990s of the past century, cartilage tissue engineering using ACI has been used in thousands of patients to repair articular cartilage defects.
Liliana S, Moreira-Teixeira   +4 more
  +5 more sources

Cartilage Tissue Engineering: An Introduction

2022
Once damaged, cartilage has limited healing capability. This has led to a huge body of research that aims to repair or regenerate this important tissue. Despite the progress made, significant hurdles still need to be overcome. This chapter highlights some of the progress made, while elaborating on areas that need further research.
Martin J, Stoddart   +2 more
openaire   +2 more sources

Transplanted Tissue-Engineered Cartilage

Archives of Facial Plastic Surgery, 2006
To evaluate the feasibility of transplanting sculpted autogenous tissue-engineered cartilage (TEC) with the hope that it will retain precise 3-dimensional morphologic features after transplantation. Transplanted TEC is described in terms of the gross morphologic and histologic characteristics in contrast to pretransplanted TEC.Synthetic scaffolds of a ...
J Jared, Christophel   +2 more
openaire   +2 more sources

Bone And Cartilage Tissue Engineering

Clinics in Plastic Surgery, 1999
Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy.
B D, Boyan   +3 more
openaire   +2 more sources

Cartilage Tissue Engineering

2004
Cartilage damage is of great clinical consequence given the tissue’s limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full function or return the tissue to its native normal state.
Gamze, Torun Köse, Vasif, Hasirci
openaire   +2 more sources

Scaffolds for Tissue Engineering of Cartilage

Critical Reviews™ in Eukaryotic Gene Expression, 2002
Articular cartilage lesions resulting from trauma or degenerative diseases are commonly encountered clinical problems. It is well-established that adult articular cartilage has limited regenerative capacity, and, although numerous treatment protocols are currently employed clinically, few approaches exist that are capable of consistently restoring long-
T B F, Woodfield   +4 more
openaire   +2 more sources

Mechanobioreactors for Cartilage Tissue Engineering

2015
Mechanical stimulation is an effective method to increase extracellular matrix synthesis and to improve the mechanical properties of tissue-engineered cartilage constructs. In this chapter, we describe valuable methods of imposing direct mechanical stimuli (compression or shear) to tissue-engineered cartilage constructs as well as some common ...
Joanna F, Weber   +2 more
openaire   +2 more sources

The Role of Bioreactors in Cartilage Tissue Engineering

Current Stem Cell Research & Therapy, 2012
Cartilage tissue engineering is concerned with developing in vitro cartilage implants that closely match the properties of native cartilage, for eventual implantation to replace damaged cartilage. The three components to cartilage tissue engineering are cell source, such as in vitro expanded autologous chondrocytes or mesenchymal progenitor cells, a ...
Mabvuure, Nigel   +2 more
openaire   +3 more sources

Injectable cartilage tissue engineering

Expert Opinion on Biological Therapy, 2004
Cartilage is the tissue that lines the surface of bones in articulating joints, allowing painless joint movement. Cartilage loss is an increasingly significant problem, particularly with the ageing of active baby boomers, with few efficacious treatments available at present.
openaire   +2 more sources

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