Results 151 to 160 of about 6,791,525 (193)
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2004
Cartilage damage is of great clinical consequence given the tissue’s limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full function or return the tissue to its native normal state.
Gamze, Torun Köse, Vasif, Hasirci
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Cartilage damage is of great clinical consequence given the tissue’s limited intrinsic potential for healing. Current treatments for cartilage repair are less than satisfactory, and rarely restore full function or return the tissue to its native normal state.
Gamze, Torun Köse, Vasif, Hasirci
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Scaffolds for Tissue Engineering of Cartilage
Critical Reviews in Eukaryotic Gene Expression, 2002Articular cartilage lesions resulting from trauma or degenerative diseases are commonly encountered clinical problems. It is well-established that adult articular cartilage has limited regenerative capacity, and, although numerous treatment protocols are currently employed clinically, few approaches exist that are capable of consistently restoring long-
T B F, Woodfield +4 more
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Bone And Cartilage Tissue Engineering
Clinics in Plastic Surgery, 1999Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centered on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy.
B D, Boyan +3 more
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Mechanobioreactors for Cartilage Tissue Engineering
2015Mechanical stimulation is an effective method to increase extracellular matrix synthesis and to improve the mechanical properties of tissue-engineered cartilage constructs. In this chapter, we describe valuable methods of imposing direct mechanical stimuli (compression or shear) to tissue-engineered cartilage constructs as well as some common ...
Joanna F, Weber +2 more
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The Role of Bioreactors in Cartilage Tissue Engineering
Current Stem Cell Research & Therapy, 2012Cartilage tissue engineering is concerned with developing in vitro cartilage implants that closely match the properties of native cartilage, for eventual implantation to replace damaged cartilage. The three components to cartilage tissue engineering are cell source, such as in vitro expanded autologous chondrocytes or mesenchymal progenitor cells, a ...
Mabvuure, Nigel +2 more
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Microbioreactors for Cartilage Tissue Engineering
2015In tissue engineering research, cell-based assays are widely utilized to fundamentally explore cellular responses to extracellular conditions. Nevertheless, the simplified cell culture models available at present have several inherent shortcomings and limitations.
Yu-Han, Chang, Min-Hsien, Wu
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Injectable cartilage tissue engineering
Expert Opinion on Biological Therapy, 2004Cartilage is the tissue that lines the surface of bones in articulating joints, allowing painless joint movement. Cartilage loss is an increasingly significant problem, particularly with the ageing of active baby boomers, with few efficacious treatments available at present.
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Bioreactors for Tissue Engineering of Cartilage
2008The cartilage regenerative medicine field has evolved during the last decades. The first-generation technology, autologous chondrocyte transplantation (ACT) involved the transplantation of in vitro expanded chondrocytes to cartilage defects. The second generation involves the seeding of chondrocytes in a three-dimensional scaffold.
S, Concaro, F, Gustavson, P, Gatenholm
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Nanostructured Capsules for Cartilage Tissue Engineering
2015Polymeric multilayered capsules (PMCs) have found great applicability in bioencapsulation, an evolving branch of tissue engineering and regenerative medicine. Here, we describe the production of hierarchical PMCs composed by an external multilayered membrane by layer-by-layer assembly of poly(L-lysine), alginate, and chitosan.
Correia, Clara R. +2 more
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Gradients in articular cartilage and cartilage tissue engineering
Journal of Biomaterials Science, Polymer EditionArticular cartilage (AC) possesses complex depth-dependent gradients in cell phenotype, matrix composition, metabolism, mechanics, and growth factors. These natural gradients are essential for cartilage function. Because of lack of blood vessels, the repair and treatment of AC defects have been a grand challenge for surgeons, the natural gradients ...
Wei, Zhou +3 more
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