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Biological and Pharmacological Activities of Carvacrol and Carvacrol Bearing Essential Oils

Current Pharmaceutical Design, 2008
Oregano essential oils obtained from the genera Origanum, Thymus, Coridothymus, Thymbra, Satureja and Lippia are rich in carvacrol, a monoterpenic phenol isomeric with thymol. Turkey is the biggest exporter of oregano herb and oil to the world markets. Oregano is mainly used in food, spice and pharmaceutical industries. Carvacrol is responsible for the
Başer, K. Hüsnü Can
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Carvacrol and human health: A comprehensive review

Phytotherapy Research, 2018
Carvacrol (CV) is a phenolic monoterpenoid found in essential oils of oregano (Origanum vulgare), thyme (Thymus vulgaris), pepperwort (Lepidium flavum), wild bergamot (Citrus aurantium bergamia), and other plants. Carvacrol possesses a wide range of bioactivities putatively useful for clinical applications such antimicrobial, antioxidant, and ...
Mehdi Sharifi-Rad, Elena Maria Varoni, Marcello Iriti   +2 more
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The Bioactivity and Toxicological Actions of Carvacrol

Critical Reviews in Food Science and Nutrition, 2014
Carvacrol is a monoterpenic phenol produced by an abundant number of aromatic plants, including thyme and oregano. Presently, carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations.
Zacharias E, Suntres, John, Coccimiglio, Misagh, Alipour   +2 more
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The effect of carvacrol on enteric viruses

International Journal of Food Microbiology, 2015
Carvacrol, a monoterpenic phenol, is said to have extensive antimicrobial activity in a wide range of food spoilage or pathogenic fungi, yeast and bacteria. The aim of this study was to assess its antiviral activity on norovirus surrogates, feline calicivirus (FCV), murine norovirus (MNV), and hepatitis A virus (HAV), as well as its potential in food ...
C, Sánchez, R, Aznar, G, Sánchez
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Biological Efficacy of Carvacrol Analogues

Recent Patents on Anti-Infective Drug Discovery, 2019
Carvacrol is the major constituent of essential oils derived from plants. It exhibits antimicrobial, antioxidant, anticancer, anti-inflammatory, and anticholinesterase activity. The analogues of carvacrol can be prepared via selected synthetic routes, resulting in potent compounds.Modifying carvacrol by the introduction of selected functionalities has ...
Zintle, Mbese, Blessing Atim, Aderibigbe
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Structural Requirements for the Antimicrobial Activity of Carvacrol

Journal of Agricultural and Food Chemistry, 2006
Carvacrol is a component of several essential oils and has been shown to exert antimicrobial activity. The structural requirements for the activity of carvacrol were determined by comparison to structurally related (nonessential oil) compounds. Removal of the aliphatic ring substituents of carvacrol slightly decreased the antimicrobial activity.
Veldhuizen, E.J.A., Tjeerdsma - van Bokhoven, J.L.M., Zweijtzer, C., Burt, S.A., Haagsman, H.P.   +4 more
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Isopropoxy‐Carvacrol, a Derivative Obtained from Carvacrol, Reduces Acute Inflammation and Nociception in Rodents

Basic & Clinical Pharmacology & Toxicology, 2014
AbstractMonoterpenes, compounds mainly presented in essential oils, have important pharmacological actions. Isopropoxy‐carvacrol (IPC) is a derivative of the monoterpene carvacrol, and its pharmacological properties have not yet been investigated. The aim of this study was to analyse the acute anti‐inflammatory and antinociceptive properties of IPC ...
Rangel R, Bonfim, Igor O, Paiva-Souza, Janaína P, Moraes, Denyson S, Pereira, Cliomar A, Santos, Danielle G, Santana, Sara M, Thomazzi, Jamile N S, Ferro, Emiliano O, Barreto, Damião P, Sousa, Enilton A, Camargo   +10 more
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Synthesis and Pharmacological Evaluation of Carvacrol Propionate

Inflammation, 2014
This study aimed at synthesizing the carvacrol propionate (CP) and evaluating its pharmacological profile. CP was obtained from carvacrol and propionyl chloride through an esterification reaction. Male Swiss mice were treated with CP (25, 50, or 100 mg/kg). We evaluated the analgesic effect, mechanical hyperalgesia, and anti-inflammatory effect.
Marilia Trindade, de Santana, Viviane Barros, Silva, Renan Guedes, de Brito, Priscila Laíse, dos Santos, Sócrates Cabral, de Holanda Cavalcanti, Emiliano Oliveira, Barreto, Jamylle Nunes, de Souza Ferro, Márcio Roberto Viana, dos Santos, Adriano Antunes, de Sousa Araújo, Lucindo José, Quintans-Júnior   +9 more
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Carvacrol‐rich plants in Greece

Flavour and Fragrance Journal, 1989
AbstractThe species which grow wild and are used as oregano in Greece are Coridothymus capltatus (L.) Reichenb. fil., Satureja thymbra L., Origanum onites L. and O. vulgare L. Because of their economic importance, we studied their distribution in Greece and their essential oils.
S. Kokkini, D. Vokou
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Pharmacological Effects of Carvacrol in In vitro Studies: A Review

Current Pharmaceutical Design, 2018
Carvacrol has a high therapeutic potential, with in vitro studies showing promising results in different cellular models using a variety of methodological designs. Therefore, the objective of this study was to conduct a systematic review to analyze the pharmacological effects of carvacrol in in vitro studies.
Erika Ramos, Silva, Fernanda Oliveira, de Carvalho, Luciana Garcez Barretto, Teixeira, Nayara Gomes Lima, Santos, Fernanda Araújo, Felipe, Hericalizandra Santa Rosa, Santana, Saranavan, Shanmugam, Lucindo José, Quintans Júnior, Adriano Antunes, de Souza Araújo, Paula Santos, Nunes   +9 more
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