Results 101 to 110 of about 194,133 (208)
Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
G3: Genes, Genomes, Genetics, 2020 Nikolay P. Kandul +5 more
doaj +1 more source
Modeling variable guide efficiency in pooled CRISPR screens with ContrastiveVI+ [PDF]
arXivGenetic screens mediated via CRISPR-Cas9 combined with high-content readouts have emerged as powerful tools for biological discovery. However, computational analyses of these screens come with additional challenges beyond those found with standard scRNA-seq analyses.
arxiv
Genome engineering using the CRISPR-Cas9 system
Nature Protocols, 2013 F. Ran +6 more
semanticscholar +1 more source
CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling [PDF]
, 2014 Randall J. Platt +20 more
openalex +1 more source
DNA targeting specificity of RNA-guided Cas9 nucleases
Nature Biotechnology, 2013 P. Hsu +13 more
semanticscholar +1 more source
Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins [PDF]
, 2014 Sojung Kim +4 more
openalex +1 more source
Development and Applications of CRISPR-Cas9 for Genome Engineering
Cell, 2014 P. Hsu, E. Lander, Feng Zhang
semanticscholar +1 more source
Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA [PDF]
, 2014 Suresh Ramakrishna +5 more
openalex +1 more source
Structural insights into Cas9 mismatch: promising for development of high-fidelity Cas9 variants
Signal Transduction and Targeted Therapy, 2022 Honghai Tang, Daqi Wang, Yilai Shu
doaj +1 more source