Results 91 to 100 of about 43,177 (231)
Investigation of a conserved tyrosine residue in a yeast casein kinase 1 protein kinase
The FASEB Journal, 2009 Yck1/2 are essential and redundant plasma membrane‐associated casein kinase 1 (CK1) proteins in budding yeast. In addition to sequence features common to protein kinases, CK1s share features unique to this subfamily. We identified the peptide HIPYRE as such a feature and investigated its role in the function of
Jessica Miller +2 more
openaire +1 more source
Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON [PDF]
Scientific Reports, 2016 AbstractIn some fibroblasts, casein kinase 1α (CK1α) is localized to nuclear speckles, which are sub-nuclear compartments supplying splicing factors, whereas it is recruited on keratin filaments in colorectal cancer cells such as DLD1 cells. In order to obtain a deeper understanding of why CK1α is localized to these different subcellular sites, we ...
Takahisa Kuga +9 more
openaire +2 more sources
Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1
, 1992 Two cDNAs encoding casein kinase-1 have been isolated from a yeast cDNA library and termed CKI1 and CKI2. Each clone encodes a protein of approximately 62,000 Da containing a highly conserved protein kinase domain surrounded by variable amino- and ...
Wang, P. C. +3 more
core +1 more source
, 2022 Circadian clocks are timing devices that rhythmically adjust organism’s behavior, physiology, and metabolism to the 24-h day-night cycle. Eukaryotic circadian clocks rely on several interlocked transcription-translation feedback loops, where protein ...
Olga Bazalova (14256296) +6 more
core +1 more source
Acta Neuropathologica CommunicationsHyperphosphorylated TDP-43 aggregates in the cytoplasm of motor neurons is a neuropathological signature of amyotrophic lateral sclerosis (ALS).
Vivian I. Ko +9 more
doaj +1 more source
Casein Kinase 1 Epsilon Regulates Glioblastoma Cell Survival. [PDF]
Sci Rep, 2018 AbstractGlioblastoma is the most common malignant brain cancer with a dismal prognosis. The difficulty in treating glioblastoma is largely attributed to the lack of effective therapeutic targets. In our previous work, we identified casein kinase 1 ε (CK1ε, also known as CSNK1E) as a potential survival factor in glioblastoma.
Varghese RT +8 more
europepmc +4 more sources
Responsive Materials, EarlyView.This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun +8 more
wiley +1 more source
Developmental changes in rat hepatic casein kinases 1 and 2 [PDF]
European Journal of Biochemistry, 1987 Cytosolic histone kinase and casein kinase activities varied considerably in the late fetal and postnatal periods of liver development. Both activities showed a maximum at day 21 of gestation and decreased at birth to values close to those of adult rats.
M, Perez, J, Grande, E, Itarte
openaire +2 more sources
, 2022 Circadian clocks are timing devices that rhythmically adjust organism’s behavior, physiology, and metabolism to the 24-h day-night cycle. Eukaryotic circadian clocks rely on several interlocked transcription-translation feedback loops, where protein ...
Olga Bazalova (14256296) +6 more
core +1 more source
Anticancer Alkaloid Lamellarins Inhibit Protein Kinases
Marine Drugs, 2008 Lamellarins, a family of hexacyclic pyrrole alkaloids originally isolated from marine invertebrates, display promising anti-tumor activity. They induce apoptotic cell death through multi-target mechanisms, including inhibition of topoisomerase I ...
Laurent Meijer +8 more
doaj +1 more source