Results 81 to 90 of about 43,522 (228)

Cyclooxygenase 2-dependent and independent activation of Akt through casein kinase 2α contributes to human bladder cancer cell survival

open access: yesBMC Urology, 2011
Background Survival rate for patients presenting muscle invasive bladder cancer is very low, and useful therapeutic target has not been identified yet. In the present study, new COX2 downstream signals involved in urothelial carcinoma cell survival were ...
Fujimoto Kiyohide   +4 more
doaj   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

open access: yesResponsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun   +8 more
wiley   +1 more source

Estradiol reverses TGF-β1–induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism

open access: yes, 2002
Estradiol reverses TGF-β1–induced mesangial cell apoptosis by a casein kinase 2-dependent mechanism.BackgroundThe slower rate of progression of chronic renal disease in women than in men is explained in part by the ability of estradiol to reverse the ...
Bognar, Istvan   +5 more
core   +1 more source

CASEIN KINASE 2 AND SURVIVIN MODULATION IN PROSTATE AND BREAST CANCER

open access: yesPakistan Armed Forces Medical Journal, 2017
Objective: To find out whether Casein Kinase 2 (CK2) and Survivin co-express and correlate in prostate as well as in breast cancer. Study Design: A cross sectional analytical study. Place and Duration of Study: Study was done at Army Medical College and
Sarah Sadiq   +4 more
doaj  

RNA sequencing identified novel target genes for in breast and colon cancer cells

open access: yesScience Progress, 2021
Adansonia digitata exhibits numerous beneficial effects. In the current study, we investigated the anti-cancer effects of four different extracts of A. digitata (polar and non-polar extracts of fruit powder and fibers) on the proliferation of human colon
Omar S. El-Masry   +4 more
doaj   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

open access: yesSmall, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Kinetics of recombinant CD98 phosphorylation by casein kinase 2.

open access: yes, 2013
Phosphorylation reactions were performed using different concentrations of recombinant CD98 and constant amounts of casein kinase 2 (CK2, 50 ng) and [γ-32P]ATP (2 µCi).
Tracy S. Obertone (265298)   +5 more
core   +1 more source

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor

open access: yesPharmaceuticals, 2017
Protein kinase CK2 is associated with a number of human diseases, among them cancer, and is therefore a target for inhibitor development in industry and academia.
Karsten Niefind   +6 more
doaj   +1 more source

Convergent digestive adaptation to resource limitation in an insular lizard across a microgeographic archipelago

open access: yesJournal of Animal Ecology, EarlyView.
Replicated mainland–islet populations of the Skyros wall lizard reveal consistent divergence in digestive physiology, including gut morphology, passage time, digestive efficiency and enzyme activity. These results show how ecological variation in resource availability can shape digestive performance across populations in insular environments.
Aikaterini Reppa   +8 more
wiley   +1 more source

Interplay of Phosphorylated Apoptosis Repressor with CARD, Casein Kinase-2 and Reactive Oxygen Species in Regulating Endothelin-1–Induced Cardiomyocyte Hypertrophy [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2013
Objective(s):  The role of the Apoptosis repressor with caspase recruitment domain (ARC) in apoptosis and in certain hypertrophic responses has been previously investigated, but its regulation of Endothelin-1 induced cardiac hypertrophy remains unknown ...
Iram Murtaza   +4 more
doaj  

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