Results 61 to 70 of about 43,522 (228)

Intricate coupling between the transactivation and basic-leucine zipper domains governs phosphorylation of transcription factor ATF4 by casein kinase 2. [PDF]

J Biol Chem, 2022
Most transcription factors possess at least one long intrinsically disordered transactivation domain that binds to a variety of coactivators and corepressors and plays a key role in modulating the transcriptional activity.
Siang S, Underbakke ES, Roche J.
europepmc   +3 more sources

Casein Kinase 2 Phosphorylation of Protein Kinase C and Casein Kinase 2 Substrate in Neurons (PACSIN) 1 Protein Regulates Neuronal Spine Formation [PDF]

Journal of Biological Chemistry, 2013
The PACSIN (protein kinase C and casein kinase 2 substrate in neurons) adapter proteins couple components of the clathrin-mediated endocytosis machinery with regulators of actin polymerization and thereby regulate the surface expression of specific receptors.
Sylvia, Schael, Julian, Nüchel, Stefan, Müller, Philipp, Petermann, Jan, Kormann, Isabel, Pérez-Otaño, Sonia Marco, Martínez, Mats, Paulsson, Markus, Plomann   +8 more
openaire   +2 more sources

Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy

Animal Models and Experimental Medicine, EarlyView.
Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan, Khushbakhat Alia, Yusra Al Dhaheri, Muhammad Naseem, Rabah Iratni, Edgar Serfling, Khalid Muhammad   +6 more
wiley   +1 more source

pH-dependent changes in structure and RNA-binding activity of casein kinase 2 from Rana temporaria oocytes

, 1991
It is demonstrated by filter-binding assay that casein kinase 2 from Rana temporaria oocytes binds rRNA in vitro with high affinity. Ligand-blotting shows that rRNA-binding activity is inherent to α and α′ subunits of the enzyme.
Obolbek A. Turapov, Aleksandr S. Stepanov, Turapov, Obolbek A., Denis V. Kapkov, Konstantin V. Kandror, Kandror, Konstantin V., Kapkov, Denis V., Stepanov, Aleksandr S.   +7 more
core   +1 more source

Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90

Cell Reports, 2019
Summary: The molecular chaperone Hsp90 stabilizes and activates client proteins. Co-chaperones and post-translational modifications tightly regulate Hsp90 function and consequently lead to activation of clients.
Rebecca A. Sager, Mark R. Woodford, Sarah J. Backe, Alan M. Makedon, Alexander J. Baker-Williams, Bryanna T. DiGregorio, David R. Loiselle, Timothy A. Haystead, Natasha E. Zachara, Chrisostomos Prodromou, Dimitra Bourboulia, Laura S. Schmidt, W. Marston Linehan, Gennady Bratslavsky, Mehdi Mollapour   +14 more
doaj   +1 more source

Protective Effect of Phytic Acid in Cardiovascular Diseases: A Systematic Review

ChemFoodChem, EarlyView.
ABSTRACT Cardiovascular diseases (CVDs) are a cluster of ailments that impact the heart and blood vessels and are a primary public health problem of mortality on a global scale. Phytic acid, a dietary constituent frequently present in foods like seeds, has been linked to many pharmacological attributes, including anti‐cancer, antioxidant, anti ...
Marta M. S. de Freitas Almeida, Éverton A. Pereira, Patricia Severino, Cristina Blanco‐Llamero, Sandra L. Santos, Luciana N. Andrade, Ricardo G. Amaral, Eliana B. Souto   +7 more
wiley   +1 more source

The decreased level of casein kinase 2 in brain cortex of schizophrenic and Alzheimer's disease patients

, 1991
The content of casein kinase 2 is considerably decreased in ribosome-free extracts of the frontal cortex of schizophrenic and Alzheimer's disease patients in comparison to normal brains as has been demonstrated by means of immunoblotting. The activity of
G.Sh. Burbaeva, Stepanov, A.S., K.V. Kandror, A.S. Stepanov, D.V. Kapkov, Kapkov, D.V., Aksenova, M.V., Kandror, K.V., Burbaeva, G.Sh., M.V. Aksenova   +9 more
core   +1 more source

sj-docx-1-asn-10.1177_17590914231158218 - Supplemental material for Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia

, 2023
Supplemental material, sj-docx-1-asn-10.1177_17590914231158218 for Casein Kinase 2 Mediates HIV- and Opioid-Induced Pathologic Phosphorylation of TAR DNA Binding Protein 43 in the Basal Ganglia by Michael Ohene-Nyako, Sara R. Nass, Hope T.
Michael Ohene-Nyako (4729965), Sara R. Nass (14766998), Kurt F. Hauser (8201931), Hope T. Richard (14767001), Robert Lukande (602521), Melanie R. Nicol (14767004), MaryPeace McRae (7592366), Pamela E. Knapp (8201928)   +7 more
core   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

Figure 3. PrP-induced fast axonal transport inhibition is mediated by Casein kinase 2 activity.

, 2017
Figure 3.
Emiliano Zamponi (4707478), Hector H. Caicedo (5013422), Helguera, Pablo R., Fiamma A. Buratti (5013431), Buratti, Fiamma A., Lisa M. Jungbauer (2418157), Pigino, Gustavo F., Alfredo Lorenzo (4707481), Bisbal, Mariano, Lorenzo, Alfredo, Scott T. Brady (413946), Morfini, Gerardo A., Gustavo F. Pigino (421118), Yuyu Song (421110), LaDu, Mary J., Song, Yuyu, Zamponi, Emiliano, Cataldi, Gabriel E., Caicedo, Hector H., Brady, Scott T., Mary J. LaDu (4707484), Ma, Jiyan, Gabriel E. Cataldi (5013428), Pablo R. Helguera (4707475), Gerardo A. Morfini (421107), Mariano Bisbal (176625), Jiyan Ma (300432), Jungbauer, Lisa M.   +27 more
core   +1 more source