Results 41 to 50 of about 43,522 (228)
Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization
Acta Neuropathologica Communications, 2022 Alzheimer’s disease (AD) is a neurodegenerative disorder that exhibits pathological changes in both tau and synaptic function. AD patients display increases in hyperphosphorylated tau and synaptic activity.
Courtney A. Marshall +5 more
doaj +1 more source
Molekulare und funktionelle Charakterisierung der Casein Kinase 2 : vergleichende Phosphoproteom- und Metabolom-Analysen [PDF]
, 2020 Das Ziel der Arbei war es die Casein Kinase 2 (CK2), eine lösliche Kinase im Stroma der Chloroplasten, umfassend molekularbiologisch und funktionell zu untersuchen.
Bergner, Elena
core +1 more source
eLife, 2020 Circadian clocks in fungi and animals are driven by a functionally conserved transcription–translation feedback loop. In Neurospora crassa, negative feedback is executed by a complex of Frequency (FRQ), FRQ-interacting RNA helicase (FRH), and casein ...
Christina M Kelliher +5 more
doaj +1 more source
Casein kinase 2 interacts with and phosphorylates ataxin-3 [PDF]
Neuroscience Bulletin, 2008 Machado-Joseph disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) is an autosomal dominant neurodegenerative disorder caused by an expansion of polyglutamine tract near the C-terminus of the MJD1 gene product, ataxin-3. The precise mechanism of the MJD/SCA3 pathogenesis remains unclear. A growing body of evidence demonstrates that phosphorylation plays
Rui-Song, Tao +4 more
openaire +2 more sources
, 2021 ATP binding site; Protein kinase casein kinase 2 (PKCK2); Selective PKCK2 ...
권영주
core +1 more source
Phosphoproteomic Landscape of AML Cells Treated with the ATP-Competitive CK2 Inhibitor CX-4945
Cells, 2021 Casein kinase 2 (CK2) regulates a plethora of proteins with pivotal roles in solid and hematological neoplasia. Particularly, in acute myeloid leukemia (AML) CK2 has been pointed as an attractive therapeutic target and prognostic marker.
Mauro Rosales +11 more
doaj +1 more source
Copper Modulates the Catalytic Activity of Protein Kinase CK2
Frontiers in Molecular Biosciences, 2022 Casein kinase 2 (CK2) is an evolutionarily conserved serine/threonine kinase implicated in a wide range of cellular functions and known to be dysregulated in various diseases such as cancer.
John E. Chojnowski +7 more
doaj +1 more source
, 2019 Casein kinase 2 and mechanisms of CK2 protein ...
Asokan Rethinaswamy (5883530)
core +1 more source
Stimulation of Eryptosis by Caspofungin
Cellular Physiology and Biochemistry, 2016 Background/Aims: The echinocandin antifungal agent caspofungin has been shown to trigger apoptosis of fungal cells. Beyond that, caspofungin is toxic for host mitochondria.
Thomas Peter +2 more
doaj +1 more source
Synthesis and cytotoxic activity of (2-arylquinazolin-4-yl)hydrazones of 2-hydroxybenzaldehydes
Chimica Techno Acta, 2023 2-Phenyl-6,7-difluoro and 2-(4-fluorophenyl)quinazoline derivatives bearing salicylidenhydrazino fragments at position 4 were prepared based on 4,5-difluoroantranilic acid or anthranilamide.
Emiliya V. Nosova +3 more
doaj +1 more source