Results 31 to 40 of about 43,522 (228)
Regulation of casein kinase 2 by phosphorylation/dephosphorylation [PDF]
Biochemical Journal, 1987 The effects of various polycation-stimulated (PCS) phosphatases and of the active catalytic subunit of the ATPMg-dependent (AMDc) protein phosphatase on the activity of casein kinase 2 (CK-2) were investigated by using the synthetic peptide substrate Ser-Glu-Glu-Glu-Glu-Glu, whose phosphorylated derivative is entirely insensitive to these protein ...
Agostinis P +3 more
openaire +2 more sources
Ck2-Dependent Phosphorylation Is Required to Maintain Pax7 Protein Levels in Proliferating Muscle Progenitors. [PDF]
PLoS ONE, 2016 Skeletal muscle regeneration and long term maintenance is directly link to the balance between self-renewal and differentiation of resident adult stem cells known as satellite cells.
Natalia González +6 more
doaj +1 more source
Casein kinase 2 controls synapse organization and stability [PDF]
, 2013 Synapse remodeling is a local and dynamic process, requiring constant modifications of the neuronal network. Post-translational modifications, such as reversible phosphorylation by kinases and phosphatases, play a crucial role in synapse development and ...
Bulat, Victoria
core +1 more source
Discovery of a Potent and Selective Naphthyridine-based Chemical Probe for Casein Kinase 2
, 2022 Naphthyridine-based inhibitors were synthesized to yield a potent and cell-active inhibitor of casein kinase 2 (CK2). Compound 2 selectively inhibits CK2⍺ and CK2⍺’ when profiled broadly, making it an exquisitely selective chemical probe for CK2.
Andreas, Krämer +11 more
core +1 more source
Neurobiology of Disease, 2015 Background and purpose: Edema formation, inflammation and increased blood–brain barrier permeability contribute to poor outcomes after intracerebral hemorrhage (ICH).
Loretta O. Iniaghe +5 more
doaj +1 more source
Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock.
PLoS ONE, 2012 Throughout the day, clock proteins synchronize changes in animal physiology (e.g., wakefulness and appetite) with external cues (e.g., daylight and food).
Lorna S Kategaya +5 more
doaj +1 more source
Efavirenz Induced Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2015 Background/Aims: The reverse transcriptase inhibitor efavirenz utilized for the treatment of human immunodeficiency virus (HIV)-1 infection, triggers suicidal cell death or apoptosis, an effect in part due to interference with mitochondrial potential ...
Rosi Bissinger +5 more
doaj +1 more source
CK2 and the Hallmarks of Cancer
Biomedicines, 2022 Cancer is a leading cause of death worldwide. Casein kinase 2 (CK2) is commonly dysregulated in cancer, impacting diverse molecular pathways. CK2 is a highly conserved serine/threonine kinase, constitutively active and ubiquitously expressed in ...
May-Britt Firnau, Angela Brieger
doaj +1 more source
Stimulating Effect of Sclareol on Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2016 Background/Aims: The diterpene alcohol Sclareol has been proposed for the treatment of malignancy. In analogy to apoptosis of nucleated cells, erythrocytes may enter eryptosis, a suicidal cell death characterized by cell shrinkage and cell membrane ...
Elena Signoretto +2 more
doaj +1 more source
Identification of Candidate Casein Kinase 2 Substrates in Mitosis by Quantitative Phosphoproteomics
Frontiers in Cell and Developmental Biology, 2017 Protein phosphorylation is a crucial regulatory mechanism that controls many aspects of cellular signaling. Casein kinase 2 (CK2), a constitutively expressed and active kinase, plays key roles in an array of cellular events including transcription and ...
Scott F. Rusin +3 more
doaj +1 more source