Results 51 to 60 of about 26,990 (272)

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

Advanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang, Shipeng Dai, Yuchen Xie, Pengyu Chen, Yue Chai, Chongyu Wang, Xueying Huang, Xiao Dong, Junfeng Shi, Yongxiang Xia, Xiaofeng Qian, Weiwei Tang, Yichan Zhou   +12 more
wiley   +1 more source

Enhancing Mechanical and Electrochemical Stability of EDLC Electrodes via Crosslinked Polysaccharide Binder Blends

Advanced Science, EarlyView.
Cross‐linked polysaccharide binders derived from potato starch and xanthan gum enable fully water processed EDLC electrodes with improved mechanical integrity and long‐term electrochemical stability at high voltage. ABSTRACT Advancing sustainable energy storage technologies has increased the focus on water processable binders for high‐performance ...
Mahdi Karimi Jafari, Rupesh Singh, Stefano Passerini, Alberto Varzi   +3 more
wiley   +1 more source

Enamel lesions: Meta-analysis on effect of prophylactic/therapeutic agents in erosive tissue loss

Journal of Dental Sciences, 2016
This study aims to perform a meta-analysis on the effect of prophylactic/therapeutic agents in enamel tissue loss due to erosion. A paper search was done on Medline, PubMed, Embase, and Cochrane Library, and 732 papers were identified.
Liliana Teixeira, Patrícia Manarte-Monteiro, Maria Conceição Manso   +2 more
doaj   +1 more source

Frequencies Evaluation of β-Casein Gene Polymorphisms in Dairy Cows Reared in Central Italy [PDF]

, 2020
Carla Sebastiani, Chiara Arcangeli, Marcella Ciullo, Martina Torricelli, Giulia Cinti, Stefano Fisichella, M. Biagetti   +6 more
openalex   +1 more source

Development in Maillard Reaction and Dehydroalanine Pathway Markers during Storage of UHT Milk Representing Differences in Casein Micelle Size and Sedimentation [PDF]

, 2022
Miguel Aguilera-Toro, Nina Aagaard Poulsen, Marije Akkerman, Valentin Rauh, Lotte Bach Larsen, Søren Drud-Heydary Nielsen   +5 more
openalex   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Identification of A1/A2 β-Casein Genotypes and Comparison of Their Digestive Properties

Shipin gongye ke-ji
A1 β-casein and A2 β-casein produce different substances after digestion due to differences in primary structure. To more comprehensively explore the possible biological activity effects on the human body, by analyzing and monitoring the changes of this ...
Shihang LI, Hongtao XU, Xiao LI, Meiling SUN, Xinyan YANG, Pengyu XIANG, Zhihao YANG, Chaoxin MAN, Yujun JIANG   +8 more
doaj   +1 more source

Novel angiotensin-converting enzyme inhibitory peptides from caseins and whey proteins of goat milk

Journal of Advanced Research, 2017
Angiotensin-converting enzyme (ACE) plays a central role in blood pressure regulation by producing the vasoconstrictor angiotensin II. The inhibition of ACE with natural inhibitors, as alternatives to avoid the side effect of synthetic drugs, is a major ...
Hisham R. Ibrahim, Ahmed S. Ahmed, Takeshi Miyata   +2 more
doaj   +1 more source

Casein genetic polymorphisms in goat breeds of Lombardy

Italian Journal of Animal Science, 2010
In the last years, the genetic polymorphism of goat caseins has raised a considerable research interest due to relationships with milk quality and technological properties (Martin et al., 2002). The four caseins, αs1-casein (CSN1S1), β-casein (
G. Pagnacco, A. Caroli, P. Bolla, F. Chiatti, S. Chessa   +4 more
doaj   +1 more source