Results 1 to 10 of about 332,479 (158)
Apoptosis and Pharmacological Therapies for Targeting Thereof for Cancer Therapeutics
Sci, 2022 Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a homeostatic balance between cell formation and cell death. It is a vital process for normal eukaryotic development as it contributes to the renewal of cells and ...
Vishakha Singh +5 more
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Viruses, 2022 A growing number of evidence shows that some invertebrates possess an antiviral immunity parallel to the interferon (IFN) system of higher vertebrates.
Kai Lǚ +6 more
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Insects, 2021 Apoptotic protease activating factor-1 (Apaf-1) is an adaptor molecule, essential for activating initiator caspase and downstream effector caspases, which directly cause apoptosis.
Haihao Ma +8 more
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Caspase-2: the orphan caspase [PDF]
Cell Death & Differentiation, 2011 Despite an abundance of literature on the role of caspase-2 in apoptosis, there exists much controversy about this protease making it difficult to place caspase-2 correctly in the apoptotic cascade, and hence its role in apoptosis remains unclear. The identification of the PIDDosome as a signaling platform for caspase-2 activation prompted intense ...
L, Bouchier-Hayes, D R, Green
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ER Stress in COVID-19 and Parkinson’s Disease: In Vitro and In Silico Evidences
Brain Sciences, 2022 The outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) signifies a serious worldwide concern to public health. Both transcriptome and proteome of SARS-CoV-2-infected cells synergize the progression of infection in
Zahara L. Chaudhry +4 more
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Molecules, 2021 Cancer has always been one of the most common malignant diseases in the world. Therefore, there is an urgent need to find potent agents with selective antitumor activity against cancer cells.
Xiaoman Ju +7 more
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Cell Death & Differentiation, 1999 Caspases are the key effector molecules of the physiological death process known as apoptosis, although some are involved in activation of cytokines, rather than cell death. They exist in most of our cells as inactive precursors (zymogens) that kill the cell once activated. Caspases can be controlled in two ways.
P G, Ekert, J, Silke, D L, Vaux
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Pharmaceuticals, 2023 In this study, a novel compound was isolated, identified, and its chemical structure was determined from the extract of the roots of Senna velutina.
David Tsuyoshi Hiramatsu Castro +8 more
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Cell Death & Differentiation, 2006 The relatively common occurrence of sequences within proteins that match the consensus substrate specificity of caspases in intracellular proteins suggests a multitude of substrates in vivo - somewhere in the order of several hundred in humans alone. Indeed, the list of proteins that are reported to be cleaved by caspases in vitro proliferates rapidly.
J C, Timmer, G S, Salvesen
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Spontaneous poisoning by Cestrum intermedium in dairy cattle
Pesquisa Veterinária Brasileira, 2021 : Acute hepatotoxicity caused by plants poisoning is responsible for economic losses in farm animals in Brazil. Reports of Cestrum intermedium natural poisoning in cattle are not commonly described in Rio Grande do Sul (RS).
Camila B. Pohl +10 more
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