Results 11 to 20 of about 628,785 (360)
Pharmaceuticals, 2023 In this study, a novel compound was isolated, identified, and its chemical structure was determined from the extract of the roots of Senna velutina.
David Tsuyoshi Hiramatsu Castro +8 more
doaj +1 more source
Caspase-3/-6/-8 are required for Gsdme-dependent pyroptosis. [PDF]
, 2022 a Images and cell viability of WT, Nlrp3-/-, Caspase-1-/- and Gsdmd-/- BMDMs left untreated or stimulated with ATP and silica. Arrowheads indicate pyroptotic cells. The scale bar represents 100 μm.
Yujie Zou (408340) +12 more
core +1 more source
Spontaneous poisoning by Cestrum intermedium in dairy cattle
Pesquisa Veterinária Brasileira, 2021 : Acute hepatotoxicity caused by plants poisoning is responsible for economic losses in farm animals in Brazil. Reports of Cestrum intermedium natural poisoning in cattle are not commonly described in Rio Grande do Sul (RS).
Camila B. Pohl +10 more
doaj +1 more source
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia. [PDF]
, 2014 The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. An unexpected role of caspase-
Rodhe, J +11 more
core +1 more source
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.
Cell, 1998 We report here that BID, a BH3 domain-containing proapoptotic Bcl2 family member, is a specific proximal substrate of Casp8 in the Fas apoptotic signaling pathway.
Honglin Li +3 more
semanticscholar +1 more source
Uterine Endoplasmic Reticulum Stress and Its Unfolded Protein Response May Regulate Caspase 3 Activation in the Pregnant Mouse Uterus [PDF]
, 2013 We have previously proposed that uterine caspase-3 may modulate uterine contractility in a gestationally regulated fashion. The objective of this study was to determine the mechanism by which uterine caspase-3 is activated and consequently controlled in ...
Subedi, Kalpana +12 more
core +1 more source
Defining Characteristics of Types I and II Apoptotic Cells in Response to TRAIL
Neoplasia: An International Journal for Oncology Research, 2002 Type I cells have been defined to be independent of mitochondria for the induction of Fas death receptormediated apoptosis, whereas Type II cells are mitochondria-dependent.
Nesrin Özören, Wafik S. El-Deiry
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Background and AimsThe development of multi-organ injury in cirrhosis is associated with increased intestinal permeability, translocation of gut-derived bacterial products [e.g., lipopolysaccharide (LPS)] into the circulation, and increased non-apoptotic
Ugo Soffientini +24 more
doaj +1 more source
, 2019 Caspase-3 activity in the hippocampus (CA1, DG), medial amygdala (MA) and lateral amygdala (LA) of the different groups. Caspase-3 activity was lower in the B.
Thomas A. Tompkins (2695411) +5 more
core +1 more source
Caspase-1 activation with concomitant degradation of cullin-1/5. [PDF]
, 2021 (A)THP-1 macrophages were incubated with Eh (10:1 ratio) for increasing time (5 to 30 min) and or /with the pan-caspase inhibitor Z-VAD-fmk (100μM) and caspase-1 specific inhibitor Z-YVAD-fmk (100μM) for 1 h followed by stimulation with Eh (10:1 ratio ...
Kris Chadee (249039) +4 more
core +1 more source