Results 161 to 170 of about 24,095,126 (372)
Dental Journal, 2019 Background: Inflammation of the pericorona due to lower third molar impaction (LTMI) is often diagnosed as pericoronitis. Expression of cyclooxigenase-2 (COX-2) and caspase-1 may be induced by lipopolysacharide (LPS) and cause pyroptosis with minimal ...
Adi Prayitno
doaj +1 more source
Advanced Functional Materials, EarlyView.Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro +7 more
wiley +1 more source
Subversion of inflammasome activation and pyroptosis by pathogenic bacteria
Frontiers in Cellular and Infection Microbiology, 2013 Activation of the inflammasome occurs in response to a notably high number of pathogenic microbes and is a broad innate immune response that effectively contributes to restriction of pathogen replication and generation of adaptive immunity. Activation of
Larissa D Cunha, Dario S Zamboni
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Caspase-9 and APAF-1 form an active holoenzyme [PDF]
, 1999 Joe Rodriguez, Yuri Lazebnik
openalex +1 more source
Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 [PDF]
, 1999 Kohji Moriishi +3 more
openalex +1 more source
Microvesicular Caspase-1 Mediates Lymphocyte Apoptosis in Sepsis
PLoS ONE, 2014 Immune dysregulation during sepsis is poorly understood, however, lymphocyte apoptosis has been shown to correlate with poor outcomes in septic patients. The inflammasome, a molecular complex which includes caspase-1, is essential to the innate immune response to infection and also important in sepsis induced apoptosis.
Matthew C. Exline +7 more
openaire +5 more sources
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Study on Anti-cancer Effect of Plant Extract ACA-1 on Gastric Adenocarcinoma Cell Line
Journal of Medicinal Plants, 2012 Background: Apoptosis provides solutions for the treatment of cancers and its induction is used as a strategy for preparing drugs that destroy pre-neoplastic cells. Many plant compounds have anti-tumoral activity.
T Ghazanfari +3 more
doaj
HIV-1 release requires Nef-induced caspase activation
PLoS ONE, 2023 HIV infection remains incurable to date and there are no compounds targeted at the viral release. We show here HIV viral release is not spontaneous, rather requires caspases activation and shedding of its adhesion receptor, CD62L.
Jason Segura +9 more
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