Results 271 to 280 of about 318,537 (297)

Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis. [PDF]

Front Pharmacol
Liu Z, Lv L, Wei J, Xie Y, Jili M, Huang Y, Yang R, Luo Y.   +7 more
europepmc   +1 more source

Increased serum caspase-1 in adult-onset Still's disease. [PDF]

PLoS One
Matsumoto H, Yoshida S, Koga T, Fujita Y, Sumichika Y, Saito K, Temmoku J, Asano T, Sato S, Mizokami M, Sugiyama M, Migita K.   +11 more
europepmc   +1 more source

A new type of Caspase-1 upon recognizing bacteria inhibits GSDME-dependent histone modification and NF-κB signaling. [PDF]

Commun Biol
Chang R, Sun J, Leng J, Wang Z, Mu S, Li Y, Wang J, Song L.   +7 more
europepmc   +1 more source

Caspase-1-licensed pyroptosis drives dsRNA-mediated necroptosis and dampens host defense against bacterial pneumonia. [PDF]

PLoS Pathog
Luo Q, Shen L, Yang S, Zhang Y, Pan Y, Wu Z, Shu Q, Chen Q.   +7 more
europepmc   +1 more source

Correction to "Adipose Tissue IL-18 Production Is Independent of Caspase-1 and Caspase-11". [PDF]

Immun Inflamm Dis
europepmc   +1 more source

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Caspase-1 activation by Salmonella

Trends in Cell Biology, 2003
Salmonella is an interesting example of how the selective pressure of host environments has led to the evolution of sophisticated bacterial virulence mechanisms. This microbe exploits the first-line of defence, the macrophage, as a crucial tool in the initiation of disease.
Järveläinen, H., Galmiche, A., Zychlinsky, A.   +2 more
openaire   +3 more sources

Assessing Caspase-1 Activation

2016
The caspase-1 enzymatic activity plays a major role in the innate immune response as it regulates the maturation of two major proinflammatory cytokines, the interleukin-1beta (IL-1β) and IL-18. In this chapter, we describe the technique of Western blot to assess caspase-1 activation. This method provides multiple information within one experiment.
Guey, B., Petrilli, V.
openaire   +2 more sources

Immunoblotting for Active Caspase-1

2013
Immunoblotting for caspase-1 is the gold-standard method of detecting inflammasome activation. In contrast to IL-1β-based readouts, it can be used in an experimental setup independent of de novo gene expression. Here, we present protocols for the preparation and precipitation of supernatant samples containing activated caspase-1 as well as protocols ...
Christopher, Jakobs, Eva, Bartok, Andrej, Kubarenko, Franz, Bauernfeind, Veit, Hornung   +4 more
openaire   +2 more sources