Results 271 to 280 of about 24,095,126 (372)

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

, 2000
Piera Pasinelli, Megan K. Houseweart, Robert H. Brown, Don W. Cleveland   +3 more
openalex   +1 more source

Interferon γ inhibits growth of human pancreatic carcinoma cells via caspase-1 dependent induction of apoptosis [PDF]

, 2001
Katharina Detjen, Katrin Farwig, Martina Welzel, Bertram Wiedenmann, Stefan Rosewicz   +4 more
openalex   +1 more source

Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides

Journal of Immunology, 2016
Hana M. Russo, Joseph K. Rathkey, A. Boyd-Tressler, Michael A. Katsnelson, Derek W. Abbott, G. Dubyak   +5 more
semanticscholar   +1 more source

Gasdermin D‐Mediated Pyroptosis Exerts Two Opposite Effects of Resisting Enzymatic Digestion and Expanding Inflammatory Response in Acute Pancreatitis

Advanced Science, EarlyView.
Gasdermin D (GSDMD) does not only reduce pancreatic enzyme synthesis but also induces pancreatic acinar cells to express mucin 1 (MUC1), which forms a barrier to prevent digestive enzyme‐mediated digestion. However, GSDMD can promote the secretion of inflammatory cytokines by macrophages and aggravate pancreatic histological injury by expanding ...
Chaoxu Liu, Ning Liang, Chen Wu, Zhaoyan Qiu, Qian Huang, Xiaolong Wei, Shurong Zhang, Shuanghong Lei, Tao Yang, Gang Wang, Qian Wang   +10 more
wiley   +1 more source

Dataset on potential biochemical activities of Cylo phe-Ala-Asp-Gly-based compounds as Caspase 1 inhibitor. [PDF]

Data Brief
Olujinmi FE, Ajaelu CJ, Akintelu SA, Oyebamiji AK.   +3 more
europepmc   +1 more source

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

, 2000
Yunyi Wei, Ted Fox, Steve P. Chambers, JoAnne Sintchak, Joyce T. Coll, Julian M.C. Golec, Lora Swenson, Keith P. Wilson, Paul S. Charifson   +8 more
openalex   +1 more source

Differential Expression of Apoptotic Protease-Activating Factor-1 and Caspase-3 Genes and Susceptibility to Apoptosis during Brain Development and after Traumatic Brain Injury [PDF]

, 2001
Alexander G. Yakovlev, Katsuya Ota, Geping Wang, Vilen Movsesyan, Weili Bao, Koichiro Yoshihara, Alan I. Faden   +6 more
openalex   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

Advanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai, Shasha Zhang, Mingchen Dai, Pei Jiang, Jingyuan Huang, Hairong Xiao, Yanqin Lin, Xujun Tang, Wei Tong, Jun He, Qiuyue Mao, Yintao Wang, Zixuan Ye, Tian Wang, Renjie Chai   +14 more
wiley   +1 more source

Sodium butyrate alleviates spinal cord injury via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis. [PDF]

Metab Brain Dis
Cui Y, Cen Q, Feng J, Wei J, Wang L, Chang C, Pang R, Wang J, Zhang A.   +8 more
europepmc   +1 more source

HIV-1 Tat Induces Microvascular Endothelial Apoptosis Through Caspase Activation [PDF]

, 2001
In-Woo Park, Christina Ullrich, Elena S. Schoenberger, Ramesh K. Ganju, Jerome E. Groopman   +4 more
openalex   +1 more source