Results 271 to 280 of about 11,510,202 (303)
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International Journal of Colorectal Disease, 2004
Hereditary nonpolyposis colorectal cancer (HNPCC) and a subset of sporadic colorectal cancers are characterized by microsatellite instability (MSI) and inactivating frameshift mutations of target genes. Inactivation of BAX, caspase-5 ( cas-5), and other genes coding for pro-apoptotic proteins might contribute to tumor progression by enhancing escape ...
Jörg Trojan
exaly +4 more sources
Hereditary nonpolyposis colorectal cancer (HNPCC) and a subset of sporadic colorectal cancers are characterized by microsatellite instability (MSI) and inactivating frameshift mutations of target genes. Inactivation of BAX, caspase-5 ( cas-5), and other genes coding for pro-apoptotic proteins might contribute to tumor progression by enhancing escape ...
Jörg Trojan
exaly +4 more sources
Journal of Cellular Physiology, 2019
In our previous studies, programmed cell death (PCD) was induced in human periodontal ligament (PDL) cells, through activation of caspase‐3 and upregulation of CASP5 gene (encoding caspase‐5 protein), in response to mechanical stretch loading. The aim of
Yaqin Wu +3 more
semanticscholar +3 more sources
In our previous studies, programmed cell death (PCD) was induced in human periodontal ligament (PDL) cells, through activation of caspase‐3 and upregulation of CASP5 gene (encoding caspase‐5 protein), in response to mechanical stretch loading. The aim of
Yaqin Wu +3 more
semanticscholar +3 more sources
Somatic mutation of the Caspase-5 gene in human lung cancer.
International Journal of Molecular Medicine, 2003Using cDNA array-based gene expression profiling, we previously found reduced expression of the Caspase-5 gene in highly metastatic subpopulations of a lung cancer cell line. The Caspase-5 gene contained poly(A) repeats in its coding region, an area that has been reported to be mutated in both endometrial and gastrointestinal tumors displaying evidence
Y. Hosomi +9 more
semanticscholar +3 more sources
Inflammatory caspases are innate immune receptors for intracellular LPS
Nature, 2014Jianjin Shi, Yue Zhao, Yupeng Wang
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Association of angiopoietin-1, angiopoietin-2 and caspase-5 polymorphisms with psoriasis vulgaris
Clinical and Experimental Dermatology, 2015Psoriasis involves a multifaceted interplay of keratinocytes, blood vessels, immune system mediators and expressed genes.To determine whether genetic polymorphisms in the angiopoietin-1 (ANGPT1), angiopoietin-2 (ANGPT2) and caspase-5 (CASP5) genes are associated with an increased risk of developing psoriasis vulgaris (PV) in a Han population in ...
Lei He
exaly +3 more sources
Mechanistic insights from inflammasome structures
Nature Reviews ImmunologyJianing Fu, Assoc Prof Kate Schroder
exaly +2 more sources