Results 111 to 120 of about 274,264 (283)
Serine protease inhibitors suppress cytochrome c-mediated caspase-9 activation and apoptosis during hypoxia‒reoxygenation [PDF]
, 2000 Zheng Dong +4 more
openalex +1 more source
Advanced Functional Materials, EarlyView.A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang +8 more
wiley +1 more source
Regulation of Caspase-9 by Natural and Synthetic Inhibitors
, 2012 Tight regulation of caspase-9, a key initiator of apoptosis, is required to uphold cellular homeostasis. Although it is controlled on a multifactorial level, misregulation of this process does occur, which is a characteristic of a variety of diseases from ischemic injury to cancer.
openaire +3 more sources
Advanced Functional Materials, EarlyView.Buckling‐resistant and trace‐stacked (BRATS) intracortical microelectrode arrays (MEAs) eliminate the need for insertion aid and complex surgical setup, resulting in minimal inflammatory tissue response, compared to conventional flexible MEAs inserted with aid. Trace stacking effectively doubled the channel count without increasing the MEA shank width,
May Yoon Pwint, Delin Shi, X. Tracy Cui
wiley +1 more source
Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells. [PDF]
Biochim Biophys Acta Gen Subj, 2023 Chakraborty S +6 more
europepmc +1 more source
Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9 [PDF]
, 2000 Qihong Huang +6 more
openalex +1 more source
Engineering Highly Cellularized Living Materials via Mechanical Agitation
Advanced Functional Materials, EarlyView.A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani +9 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This research introduces a cold plasma‐based platform for treating breast cancer bone metastases. Using a novel bioprinted 3D tumor‐stroma model, it highlights the selective antitumor effects of plasma‐generated reactive species. The platform aims to advance non‐invasive therapeutic strategies, offering potential clinical applications in controlling ...
Laura M. Bouret +4 more
wiley +1 more source
A Unique Downstream Estrogen Responsive Unit Mediates Estrogen Induction of Proteinase Inhibitor-9, a Cellular Inhibitor of IL-1β- Converting Enzyme (Caspase 1) [PDF]
, 2001 Sacha A. Krieg +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source