Results 121 to 130 of about 514,126 (359)
eLife, 2016 Caspase-3 carries out the executioner phase of apoptosis, however under special circumstances, cells can survive its activity. To document systematically where and when cells survive caspase-3 activation in vivo, we designed a system, CasExpress, which ...
Xun Ding +5 more
doaj +1 more source
Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide [PDF]
, 1998 Elizabeth Sweeney +2 more
openalex +1 more source
The Molecular Perspective: Caspases [PDF]
STEM CELLS, 2000 accidental injury, they undergo a traumatic death, swelling and bursting and flooding their surroundings with their internal components. The area then becomes inflamed as the body cleans up this necrotic mess. But cells may also undergo a controlled, antiseptic death termed “apoptosis” or “programmed cell death.” When given the signal, a cell will shut
openaire +4 more sources
Advanced Functional Materials, EarlyView.FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu +5 more
wiley +1 more source
Editorial: Gasdermins in the defense against pathogens
Frontiers in Immunology, 2023 Leopold Eckhart, Ruochan Chen
doaj +1 more source
Exploring caspase-dependent non-lethal cellular processes using Drosophila
Frontiers in Cell DeathCaspases are cysteine aspartic acid proteases conserved in animals that not only execute apoptosis, but also regulate diverse cellular processes independent of apoptosis, which are termed caspase-dependent non-lethal cellular processes (CDPs).
Natsuki Shinoda, Masayuki Miura
doaj +1 more source
Caspases‐3 and ‐7 are activated in goniothalamin‐induced apoptosis in human Jurkat T‐cells [PDF]
, 1999 Salmaan H. Inayat‐Hussain +6 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao +8 more
wiley +1 more source
Immunohistochemical Analysis of Interleukin-1β–Converting Enzyme/Ced-3 Family Protease, CPP32/Yama/Caspase-3, in Hodgkin's Disease [PDF]
, 1997 Mukesh Chhanabhai +5 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source