Results 121 to 130 of about 333,383 (311)
Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl‐2 action [PDF]
Nobuhiro Morishima
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Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang+5 more
wiley +1 more source
Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases [PDF]
Beni B. Wolf, Douglas R. Green
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Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu+7 more
wiley +1 more source
Caspase-9 and APAF-1 form an active holoenzyme [PDF]
Joe Rodriguez, Yuri Lazebnik
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The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp+5 more
wiley +1 more source
The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases [PDF]
Michael H. Cardone+4 more
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Stress is associated with broad changes in blood and immune cell dysfunction, which are correlated with the spleen as a secondary lymphoid organ. Anthocyanin, a plant bioactive compound from purple sweet potatoes, has previously been reported to have a ...
Nia Kurnianingsih+4 more
doaj +1 more source
Schematic diagram of the working model of TRAF3IP3 in the coordination of ER stress and autophagy related apoptosis in lung cancer cells. Abstract TNF receptor‐associated factor 3 interacting protein 3 (TRAF3IP3/T3JAM) exhibits dual roles in cancer progression. While upregulated in most malignancies and critical for immune regulation.
Guang Zhao+11 more
wiley +1 more source
Caspase-dependent Cleavage of Signaling Proteins during Apoptosis [PDF]
Christian Widmann+2 more
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