Results 11 to 20 of about 333,383 (311)
Inhibitors of apoptosis: expression and regulation in the endometrium during the estrous cycle and at the maternal-conceptus interface during pregnancy in pigs [PDF]
Animal Bioscience, 2022 Objective Caspase-mediated apoptosis plays a crucial role in the regulation of endometrial and placental function in females. Caspase activity is tightly controlled by members of the inhibitors of apoptosis proteins (IAPs) family. However, the expression
Inkyu Yoo +4 more
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Induction of Apoptosis in HeLa Cervical Cancer Cells Treated with Aqueous and Supercritical Fluid Extracts of Quercus infectoria [PDF]
Research Journal of Pharmacognosy, 2021 Background and objectives: The anticancer properties of extracts from Quercus infectoria galls have been demonstrated in a range of cancer cells, including human cervical cancer cells.
Hasmah Abdullah* +2 more
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Pyroptosis and respiratory diseases: A review of current knowledge
Frontiers in Immunology, 2022 Pyroptosis is a relatively newly discovered programmed cell death accompanied by an inflammatory response. In the classical view, pyroptosis is mediated by caspases-1,-4,-5,-11 and executed by GSDMD, however, recently it was demonstrated that caspase-3 ...
Jialiang Sun, Yanan Li
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eLife, 2021 Gliomas are highly malignant brain tumors with poor prognosis and short survival. NAD+ has been shown to impact multiple processes that are dysregulated in cancer; however, anti-cancer therapies targeting NAD+ synthesis have had limited success due to ...
Jiaqi Liu +8 more
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Frontiers in Cell and Developmental Biology, 2022 Cold atmospheric plasma (CAP) is an emerging and promising oncotherapy with considerable potential and advantages that traditional treatment modalities lack.
Yanhong Wang +6 more
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Frontiers in Pharmacology, 2021 Resveratrol (RES) and Vitamin E (VE) are anti-cancer active ingredients with relatively high content in peanut seeds and sprouts. This study aimed to determine the synergistic inhibitory effect of RES and VE on colorectal cancer. Using 5-FU as a positive
Chunfeng Wang +8 more
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Evaluation of Lomustine-Loaded Iron Nanoparticles on Caspase-6 Gene Expression and Cell Viability in U87Mg Cell Line [PDF]
Disease and Diagnosis, 2020 Background: Every year, many people around the world die from cancers. Among all types of cancers, brain cancer has been recognized as one of the most deadly cancers due to the late detection and limitations of current therapies, and thus it remains an ...
Zeinolabedin Sharifian Dastjerdi +8 more
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Induction of Pyroptosis: A Promising Strategy for Cancer Treatment
Frontiers in Oncology, 2021 Pyroptosis, a lytic pro-inflammatory type of programmed cell death, has been widely studied in diverse inflammatory disease models. Membrane perforation and cell swelling induced by cleaved gasdermin family members is the main characteristic of ...
Lei Wang +3 more
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Detection of Caspase Activation In Situ by Fluorochrome-Labeled Caspase Inhibitors
BioTechniques, 2001 Apoptosis is dependent on the activation of a group of proteolytic enzymes called caspases. Caspase activation can be detected by immunoblotting using caspase-specific antibodies or by caspase activity measurement employing pro-fluorescent substrates ...
P.A. Amstad +5 more
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HEPATITIS C VIRUS AND HOST CELL NUCLEAR TRANSPORT MACHINERY: A CLANDESTINE AFFAIR
Frontiers in Microbiology, 2015 There is growing evidence that factors encoded by cytoplasmic replicating viruses functionally interact with components of the nucleocytoplasmic transport apparatus.
Barbara eBonamassa +5 more
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