Results 21 to 30 of about 333,383 (311)
Frontiers in Veterinary Science, 2021 Caspases, a family of cysteine protease enzymes, are a critical component of apoptotic cell death, but they are also involved in cellular differentiation.
Wonchul Jung +8 more
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Involvement of JNK and Caspase Activation in Hoiamide A-Induced Neurotoxicity in Neocortical Neurons
Marine Drugs, 2015 The frequent occurrence of Moorea producens (formerly Lyngbya majuscula) blooms has been associated with adverse effects on human health. Hoiamide A is a structurally unique cyclic depsipeptide isolated from an assemblage of the marine cyanobacteria M ...
Zhengyu Cao +5 more
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Investigation of the cellular response to bone fractures: evidence for flexoelectricity [PDF]
Scientific Reports volume 10, Article number: 254 (2020), 2020 The recent discovery of bone flexoelectricity (electrical polarization induced by strain gradient) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We
arxiv +1 more source
Dissecting apoptosis the omics way
eLife, 2013 A combined analysis of transcription, translation and protein degradation reveals the global effects of an anticancer drug on tumour cells.
Petra Van Damme
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Non-apoptotic roles of apoptotic proteases: new tricks for an old dog [PDF]
Open Biology, 2020 This Open Question article highlights current advances in the study of non-apoptotic roles of apoptotic proteins. Apoptosis is a highly regulated and energy-requiring process in which cells actively kill themselves.
Tin Tin Su
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Global cellular response to chemotherapy-induced apoptosis
eLife, 2013 How cancer cells globally struggle with a chemotherapeutic insult before succumbing to apoptosis is largely unknown. Here we use an integrated systems-level examination of transcription, translation, and proteolysis to understand these events central to ...
Arun P Wiita +7 more
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Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death [PDF]
Apoptosis 15:401-411 (2010), 2010 In the past few years, overwhelming evidence has accrued that a high level of expression of the protein neuroglobin protects neurons in vitro, in animal models, and in humans, against cell death associated with hypoxic and amyloid insult. However, until now, the exact mechanism of neuroglobin's protective action has not been determined.
arxiv +1 more source
Armaghane Danesh Bimonthly Journal, 2022 Background & aim: Apoptosis induction is one of the basic goals in the production of anticancer drugs. Evaluation of the relationship between non-steroidal anti-inflammatory drugs (NSAID) and apoptosis in cancer cells is promising.
M Hashemzadeh, T Naji, R Ahmadi
doaj
TRAIL/Apo-2L: Mechanisms and Clinical Applications in Cancer
Neoplasia: An International Journal for Oncology Research, 2001 TNF-related apoptosis-inducing ligand (TRAIL/APO2L) is a member of the TNF family that promotes apoptosis by binding to the transmembrane receptors TRAIL-R1 /DR4 and TRAIL-R2/DR5.
Rakesh K. Srivastava
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Molecules, 2020 The seeds of Millettia ferruginea are used in fishing, pesticides, and folk medicine in Ethiopia. Here, the anti-cancer effects of isoflavones isolated from M. ferruginea were evaluated in human ovarian cancer cells.
Yi-Yue Wang +5 more
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