Results 231 to 240 of about 6,015,666 (337)

CytochromecRelease Is Upstream to Activation of Caspase-9, Caspase-8, and Caspase-3 in the Enhanced Apoptosis of Anaplastic Thyroid Cancer Cells Induced by Manumycin and Paclitaxel

, 2001
Jingxuan Pan, Guangpu Xu, Sai‐Ching J. Yeung   +2 more
openalex   +1 more source

Caspase-8 and Apaf-1-independent Caspase-9 Activation in Sendai Virus-infected Cells [PDF]

, 2002
Michael Bitzer, Sorin Armeanu, Florian Prinz, Guy Ungerechts, Wolfgang Wybranietz, Martin Spiegel, Christian Bernlöhr, Francesco Cecconi, Michael Gregor, Wolfgang J. Neubert, Klaus Schulze‐Osthoff, Ulrich M. Lauer   +11 more
openalex   +1 more source

Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy

Advanced Science, EarlyView.
This study reports for the first time an oral targeted nanomedicine that conducts ion exchange through engineered Ganoderma‐derived extracellular vesicle, managing both the in‐copper and ex‐copper in a multi‐pronged approach, offering a promising therapeutic strategy for addressing WD with reproductive dysfunction.
Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han   +12 more
wiley   +1 more source

AIP1 Regulates Ocular Angiogenesis Via NLRP12-ASC-Caspase-8 Inflammasome-Mediated Endothelial Pyroptosis. [PDF]

Adv Sci (Weinh)
Li Y, Sun Y, Xie D, Chen H, Zhang Q, Zhang S, Wen F, Ou JS, Zhang M, Su L, Li X, Wen WP, Chi W.   +12 more
europepmc   +1 more source

Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling in Activated T Cells Abrogates TRAIL-Induced Apoptosis Upstream of the Mitochondrial Amplification Loop and Caspase-8 [PDF]

, 2002
Thomas Söderström, Minna Poukkula, Tim H. Holmström, Kaisa M. Heiskanen, John Eriksson   +4 more
openalex   +1 more source

DR5 and caspase-8 are dispensable in ER stress-induced apoptosis

Cell Death and Differentiation, 2017
Jason Glab, M. Doerflinger, Christina Nedeva, Irvin Jose, George W Mbogo, J. Paton, A. Paton, Andrew J. Kueh, M. Herold, D. Huang, D. Segal, G. Brumatti, H. Puthalakath   +12 more
semanticscholar   +1 more source

Post‐Translational Modified Neoantigens in Autoimmune Diseases: Challenges of Immune Tolerance

Advanced Science, EarlyView.
Autoimmune diseases have a high incidence and disability rate. The pathogenesis of autoimmune diseases involves the interaction among genetic factors, environmental factors, and immune disorders. The post‐translational modified neoantigens are the key nodal of these three factors. And these post‐translational modified neoantigens, after being presented
Yue Zhai, Kefei Wu, Qi Lin, Zhenzhen Cao, Yankun Jia, Ping Zhu   +5 more
wiley   +1 more source

Pharmacological targeting of caspase-8/c-FLIP_L heterodimer enhances complex II assembly and elimination of pancreatic cancer cells. [PDF]

Commun Biol
König C, Ivanisenko NV, Ivanisenko VA, Kulms D, Lavrik IN.   +4 more
europepmc   +1 more source

RIPK1 blocks T cell senescence mediated by RIPK3 and caspase-8. [PDF]

Sci Adv, 2023
Imanishi T, Unno M, Yoneda N, Motomura Y, Mochizuki M, Sasaki T, Pasparakis M, Saito T.   +7 more
europepmc   +1 more source

Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain [PDF]

, 2002
Victoria H. Cowling, Julian Downward
openalex   +1 more source