Results 41 to 50 of about 455,912 (186)
Cells, 2013 Apoptotic cell death is coordinated through two distinct (type 1 and type 2) intracellular signaling pathways. How the type 1/type 2 choice is made remains a central problem in the biology of apoptosis and has implications for apoptosis related diseases ...
Somkanya C Raychaudhuri +1 more
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Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005 Determinou-se a expressão gênica das caspases 3 e 8 mediante transcrição reversa de mRNA total e reação em cadeia da polimerase (RT-PCR) para avaliar a apoptose em timo e baço de ratas imunossuprimidas por glicocorticóides.
J.J. Batista +3 more
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Unique and overlapping substrate specificities of caspase-8 and caspase-10 [PDF]
Oncogene, 2005 Although caspase-8 has an established role as an initiator of death receptor-mediated apoptosis, the function of its closest homolog, caspase-10, is almost completely unknown. To gain a closer insight into the physiological function of caspase-10, we compared the cleavage of known caspase-8 substrates by both initiator caspases.
U, Fischer, C, Stroh, K, Schulze-Osthoff
openaire +2 more sources
Irisin Protects Against Hind Limb Ischemia Reperfusion Injury
Drug Design, Development and Therapy, 2021 Ayşegül Küçük,1,* Yücel Polat,2 Aydan Kılıçarslan,3 Nuran Süngü,3 Hakan Kartal,4 Ali Doğan Dursun,5,* Mustafa Arslan6 1Kutahya Health Sciences University, Medical Faculty, Department of Physiology, Kutahya ...
Küçük A +6 more
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Journal of Translational Autoimmunity, 2020 Glucocorticoids promote thymocyte apoptosis and modulate transcription of numerous regulators of thymic apoptosis. Among these, glucocorticoid-induced leucine zipper (GILZ) is strongly upregulated in the thymus.
Isabella Muscari +8 more
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Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src. [PDF]
PLoS ONE, 2016 Src family tyrosine kinases (SFKs) phosphorylate caspase-8A at tyrosine (Y) 397 resulting in suppression of apoptosis. In addition, the phosphorylation of caspase-8A at other sites including Y465 has been implicated in the regulation of caspase-8 ...
Jennifer Ly Tsang +8 more
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FADD, Caspase-3, and Caspase-8 and Incidence of Coronary Events [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2017 Objective— To investigate the relationship between 3 markers of apoptosis, that is, FADD (Fas-associated death domain–containing protein), caspase-3, and caspase-8, and incidence of coronary events (CEs) in a population-based cohort study.
Xue L +9 more
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Caspase-3 and Caspase-8 in Patients with Nodular Goiter and Autoimmune Thyroiditis
Galician Medical Journal, 2016 The article presents results of the comparative analysis of peroxidation process activity of caspase-3 and caspase-8 in patients with thyroid adenoma (TA) and nodular goiter with autoimmune thyroiditis (NGAIT).
M. I. Sheremet +3 more
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Cell Death and Disease, 2021 Caspase-8 is a unique member of caspases with a dual role in cell death and survival. Caspase-8 expression is often lost in some tumors, but increased in others, indicating a potential pro-survival function in cancer.
Jia Xia +10 more
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Frontiers in Genetics, 2022 Postmenopausal osteoporosis (PMOP) is a systemic metabolic bone disease in postmenopausal women. It has been known that long non-coding RNAs (lncRNAs) play a regulatory role in the progression of osteoporosis.
Yongchang Yang +15 more
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