CASPASE 9 GENE EXPRESSION AND CASPASE 9 PROTEIN IN CHRONIC MYELOID LEUKEMIA IN IRAQ
The Iraqi Journal of Agricultural science, 2022 The following study was carried out to investigate gene expressions of the CASPASE 9 gene and CASPASE 9 protein with the development of chronic myeloid leukemia (CML) in Iraq.
Abdullah W. K., Maha F. A.
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Caspase-9 activates β-catenin signaling to promote pulmonary fibrosis [PDF]
Journal of Translational MedicineBackground Pulmonary fibrosis (PF) is a progressive interstitial lung disease marked by extracellular matrix accumulation and epithelial damage, with limited therapeutic options.
Juan Wang +9 more
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Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline [PDF]
Cell Death and Disease, 2022 Retinal neurovascular injuries are a leading cause of vision loss in young adults presenting unmet therapeutic needs. Neurovascular injuries damage homeostatic communication between endothelial, pericyte, glial, and neuronal cells through signaling ...
Crystal Colón Ortiz +6 more
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Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease [PDF]
Frontiers in Pharmacology, 2021 Caspase-9, a cysteine-aspartic protease known for its role as an initiator of intrinsic apoptosis, regulates physiological cell death and pathological tissue degeneration.
Maria I. Avrutsky +3 more
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Mitochondrion-Mediated Cell Death through Erk1-Alox5 Independent of Caspase-9 Signaling [PDF]
Cells, 2022 Mitochondrial disruption leads to the release of cytochrome c to activate caspase-9 and the downstream caspase cascade for the execution of apoptosis.
Min Chen +4 more
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Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h [PDF]
Pharmaceutics, 2022 The serine/threonine phosphatase PP2A and the cysteine protease Caspase 9 are two proteins involved in physiological and pathological processes, including cancer and apoptosis.
Karim Dorgham +5 more
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Caspase-9 suppresses metastatic behavior of MDA-MB-231 cells in an adaptive organoid model [PDF]
Scientific ReportsCaspase-9, a cysteine-aspartate protease traditionally associated with intrinsic apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell migration—an aspect that has received limited attention in existing studies. In our
Farzaneh Falahi +3 more
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Correction: Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline [PDF]
Cell Death and Disease, 2022 Crystal Colón Ortiz +6 more
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The therapeutic effect of conditioned medium of human amniotic membrane stem cells on heart failure in rats [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023 Background. The conditioned medium of stem cells plays an important role in the treatment of various diseases such as heart damage, but its molecular mechanisms are unknown.
Nahid Aboutaleb +4 more
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Indian Journal of Animal Sciences, 2022 The present study was conducted to evaluate the expression of caspase-3, caspase-9, growth differentiation factor-9 (GDF-9) and insulin growth factor-1 (IGF-1) genes in oocytes cultured in vitro with optimum and elevated doses of amphiregulin (50 ng and
RAMESH HONDARAVALLI SOMASHETTY +2 more
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