Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G [PDF]
Background In type 2 diabetes, free fatty acids (FFA) accumulate in microvascular cells, but the phenotypic consequences of FFA accumulation in the microvasculature are incompletely understood.
Simonson Michael S, Mishra Rangnath
doaj +4 more sources
Correction: Neurovascular injury associated non-apoptotic endothelial caspase-9 and astroglial caspase-9 mediate inflammation and contrast sensitivity decline [PDF]
Crystal Colón Ortiz +6 more
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CASPASE 9 GENE EXPRESSION AND CASPASE 9 PROTEIN IN CHRONIC MYELOID LEUKEMIA IN IRAQ
The following study was carried out to investigate gene expressions of the CASPASE 9 gene and CASPASE 9 protein with the development of chronic myeloid leukemia (CML) in Iraq.
Abdullah W. K., Maha F. A.
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The therapeutic effect of conditioned medium of human amniotic membrane stem cells on heart failure in rats [PDF]
Background. The conditioned medium of stem cells plays an important role in the treatment of various diseases such as heart damage, but its molecular mechanisms are unknown.
Nahid Aboutaleb +4 more
doaj +1 more source
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz +2 more
doaj +1 more source
TRAIL Enhances Apoptosis of Human Hepatocellular Carcinoma Cells Sensitized by Hepatitis C Virus Infection: Therapeutic Implications [PDF]
Hepatitis C virus (HCV) infection causes chronic liver diseases leading to hepatocellular carcinoma (HCC) and liver failure. We have previously shown that HCV sensitizes hepatocytes to mitochondrial apoptosis via the TRAIL death receptors DR4 and DR5 ...
Cho, Eun Kyung +12 more
core +10 more sources
GENETIC POLYMORHISM OF CASPASE 8 AND 9 IN IRAQ
This study examined the potential association between polymorphisms of Caspase 9 −293del (rs4645982) and Caspase8−652 6N ins / del (rs3834129) and the danger of acute and chronic myeloid leukaemia in Iraqi population.
Duaa Abdullah , Reema M. Aloubaidy
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(1) Background: The estimation of the post mortem interval (PMI) is a challenge for forensic pathologists because data emerging from methods commonly applied are not always conclusive, since several conditions exist that may affect the reliability of ...
Cristina Mondello +10 more
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During low tide intertidal organisms face severe temperature fluctuations. This situation may be more pronounced in the context of climate change.
Fengshen Zhao, Heding Shen
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Astaxanthin effect on apoptotic biomarkers in methotrexate-induced liver injury
Methotrexate is used in the treatment of cancer, psoriasis, rheumatoid arthritis and several other disorders. It has a hepatotoxic potential side effect. Patients who have no access to alternative medications face a serious challenge as a result.
Sarah Saad Hamdan +2 more
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