Results 191 to 200 of about 162,682 (253)

Mitochondria‐Damaging Self‐Reporting Probe for Cancer Therapy

Angewandte Chemie, EarlyView.
We developed a class of self‐reporting cationic chemotherapeutic probes that selectively induce mitochondrial damage and apoptosis in cancer cells. Their unique mitochondria‐to‐nucleus fluorescence migration enables real‐time visualization of the therapeutic process. ABSTRACT Mitochondrial damage induced by chemotherapeutic agents through disruption of
Hai Xu, Yura Lee, Sanghee Yoon, Yun Wang, Yejin Cho, Seongyu Choi, Lu Lu, Hua Zhang, Sun Choi, Ki Taek Nam, Juyoung Yoon   +10 more
wiley   +2 more sources

KIF18A inhibitor prevents chromosomally unstable osteosarcoma growth by activating spindle assembly checkpoint. [PDF]

Cancer Biol Ther
Yan Q, Zhang Y, Wang P, Fu Y, Ke C, Han S, Xing J, Li H, Zhang K.   +8 more
europepmc   +1 more source

2‐Azaazulenium Hemicyanine Dyes for NIR‐II Multimodal Imaging and Combined Phototherapy

Angewandte Chemie, EarlyView.
A strategically engineered class of 2‐azaazulenium hemicyanines is developed, featuring bright fluorescence in the second near‐infrared (NIR‐II) window and multifunctional performance. SWJT‐OCH3 shows type I/II reactive oxygen species (ROS) generation and excellent photothermal activity.
Min Peng, Bing‐Ya Wang, Hai Xu, Qiang Wang, Rong‐Dan Xiao, Rui Tan, Yu Peng, Ya‐Wen Wang, Juyoung Yoon   +8 more
wiley   +2 more sources

Effects of Lycium barbarum Residue Substituting Dietary Maize on Fecal Microbiota and Growth Performance of Crossbred Simmental Cattle

Animal Research and One Health, EarlyView.
The bioactive substances we extracted from Lycium barbarum residue (LBR) have a typical polysaccharide structure. When 1.80% LBR was used to replace maize in the diet, the average daily gain of rossbred Simmental was significantly increased, and anti‐inflammatory ability was improved. In addition, LBR improved the fecal microbial composition, increased
Kun Cai, Mingtan Li, Lihang He, Ning Ma, Haoyu Liu, Chi Xu, Xianhua Wu, Zeguang Xing, Qian Xing, Yuankai Qu, Xi Ma   +10 more
wiley   +1 more source

A novel prenylflavonoid with efficacy in cancer therapy by targeting ceramide-orchestrated signaling. [PDF]

Front Pharmacol
Du R, Zhang C, Lei H, Gao X, Xiang Q, Zhang Z, Dai Y, Li X, Zhang L, Chen G.   +9 more
europepmc   +1 more source

Ramucirumab induces apoptosis in Caco-2 cells via mitochondrial impairment and caspase activation. [PDF]

Saudi Pharm J
Al-Dogmi AM, Al-Anazi KM, Qamar W, Farah MA.   +3 more
europepmc   +1 more source

A century of cell death research. [PDF]

J Cell Sci
Green DR.
europepmc   +1 more source

Cryptocaryone Exhibits ROS/MAPK-Dependent Antiproliferative and Apoptosis-Inducing Effects on Triple-Negative Breast Cancer Cells and Proof-of-Concept Breast Cancer Mouse Model. [PDF]

Drug Dev Res
Chuang YT, Liu W, Chien TM, Farooqi AA, Chang HS, Shiau JP, Chang HW.   +6 more
europepmc   +1 more source