Results 241 to 250 of about 160,266 (354)

Rhodamine 110-Linked Amino Acids and Peptides as Substrates To Measure Caspase Activity upon Apoptosis Induction in Intact Cells

, 1999
Hubert Hug, Marek Łoś, Werner Hirt, Klaus‐Michael Debatin   +3 more
openalex   +2 more sources

Bcr-Abl Exerts Its Antiapoptotic Effect Against Diverse Apoptotic Stimuli Through Blockage of Mitochondrial Release of Cytochrome C and Activation of Caspase-3 [PDF]

, 1998
Gustavo P. Amarante-Mendes, Caryn Naekyung Kim, Linda Liu, Yue Huang, Charles Perkins, Douglas R. Green, Kapil N. Bhalla   +6 more
openalex   +1 more source

Dopant‐Regulated Piezocatalysts Evoke Sonopiezoelectric and Enzymatic PANoptosis for Synergistic Cancer Therapy

Advanced Science, EarlyView.
Engineered Mn‐substituted HfO2 (HMO) is identified with enhanced sonopiezoelectric effects and multienzymatic activities, promoting reactive oxygen species generation and amplifying oxidative stress in cancer cells. Upon ultrasound irradiation, HMO evokes cancer cell PANoptosis, thereby triggering robust antitumor immunity.
Linhong Zhong, Xun Guo, Liming Deng, Xiaoting Wang, Hongye He, Nianhong Wu, Rui Tang, Liang Chen, Yu Chen, Pan Li   +9 more
wiley   +1 more source

The concealed side of caspases: beyond a killer of cells. [PDF]

Cell Mol Life Sci
Abdelghany L, Sillapachaiyaporn C, Zhivotovsky B.   +2 more
europepmc   +1 more source

Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex [PDF]

, 1998
Dita Rasper, John P. Vaillancourt, Jamal Nasir, Vicky M. Houtzager, Isolde M. Seiden, Sabina Keen, Paul Tawa, Steve Xanthoudakis, Jamal Nasir, Duane W. Martindale, Ben F. Koop, Erin P. Peterson, Nancy A. Thornberry, Jing-Qi Huang, David MacPherson, Shawn C. Black, Felicita Hornung, Michael J. Lenardo, Michael R. Hayden, Sophie Roy, Donald W. Nicholson   +20 more
openalex   +1 more source

CCN1 Enhances Tumor Immunosuppression through Collagen‐Mediated Chemokine Secretion in Pancreatic Cancer

Advanced Science, EarlyView.
CCN1 modulates the tumor microenvironment in pancreatic cancer by promoting collagen‐dependent chemokine production, thereby facilitating immune evasion. Deletion of CCN1 not only suppresses tumor growth but also enhances immune cell infiltration and increases tumor sensitivity to both chemotherapy and immunotherapy.
Hongjie Fan, Huzi Zhao, Lili Gao, Yucheng Dong, Pei Zhang, Pengfei Yu, Yunfei Ji, Zhe‐Sheng Chen, Xinmiao Liang, Yang Chen   +9 more
wiley   +1 more source

Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

Advanced Science, EarlyView.
The multifunctional bimetallic Ca/Zn nanoagonist (PZH/Zn@CaNA) significantly downregulated the JAK2‐STAT3 signaling pathway, which effectively inhibited the proliferation and growth of HCC with incomplete microwave ablation. Furthermore, the released bimetallic ions (Ca2⁺ and Zn2⁺) synergistically enhanced oxidative stress‐mediated cytotoxicity ...
Yuan Ling, Xiayi Liang, Kangning Yan, Guichun Zeng, Xiaoqi Zhu, Jinghang Jiang, Shaolong Lu, Xiaobo Wang, Yuying Zhou, Zhaoshen Li, Wei Mai, Duo Wang, Jie Chen   +12 more
wiley   +1 more source

Targeting the inhibitors of apoptosis proteins (IAPs) to combat drug resistance in cancers. [PDF]

Front Pharmacol
Ye Q, Zhuang XZ, Li J, Zhou X.
europepmc   +1 more source

Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells

, 1998
Nobutaka Suzuki, Jun Urano, Fuyuhiko Tamanoi   +2 more
openalex   +1 more source

Caspase activation in the terminal differentiation of human epidermal keratinocytes [PDF]

, 1999
Miguel Weil, Martin Raff, Vania Braga
openalex   +1 more source