Results 281 to 290 of about 170,565 (294)

Therapeutic approaches for liver fibrosis/cirrhosis by targeting pyroptosis. [PDF]

open access: yesOpen Life Sci
Qiao G   +6 more
europepmc   +1 more source

LPS binding caspase activation and recruitment domains (CARDs) are bipartite lipid binding modules

open access: gold
Anh Cao   +7 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

open access: yesAdvanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu   +4 more
wiley   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

open access: yesAdvanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang   +14 more
wiley   +1 more source

Recurrent acquisition of nuclease-protease pairs in antiviral immunity. [PDF]

open access: yesScience
Tuck OT   +11 more
europepmc   +1 more source

Screening the Active Phytochemicals From <i>Eclipta prostrata</i> and Unraveling Their Molecular Insight Into Human Malignancies. [PDF]

open access: yesCancer Innov
Hossain MS   +13 more
europepmc   +1 more source

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