Results 111 to 120 of about 24,478 (263)

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources

Efficacy and safety of caspofungin for the treatment of invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease

Journal of International Medical Research
Objectives We assessed the efficacy of a 3-week primary or salvage caspofungin regimen in patients with chronic obstructive pulmonary disease (COPD) and concomitant proven or suspected invasive pulmonary aspergillosis (IPA).
Shaoqiang Li, Zhengtu Li, Penglei Wang, Yangqing Zhan, Jiaxing Xie, Feng Ye   +5 more
doaj   +1 more source

Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis - review of the literature

European Journal of Medical Research, 2011
Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications.
Kofla G, Ruhnke M
doaj   +1 more source

Anti-infective surface coatings: design and therapeutic promise against device-associated infections [PDF]

, 2016
Patient safety and well-being are under increasing threat from hospital-acquired infections [1]. The root cause of a large number of these infections arises from microbial biofilms that colonise on surfaces of medical devices such as the millions of ...
Coad, B., Griesser, H., Peleg, A., Traven, A.   +3 more
core   +1 more source

Predictors of caspofungin exposure-response relationship: a retrospective cohort study on therapeutic drug monitoring parameters

Frontiers in Pharmacology
IntroductionThis study aimed to characterize the exposure-response relationship of caspofungin through analysis of trough serum concentration (Cmin) associated with clinical efficacy, while identifying clinically determinants of Cmin.MethodsA single ...
Mingwei Meng, Ruhua Wei, Yating Lu, Wen Cao, Kai Mo, Zheng Huang, Yane Qin, Xiaobu Lan   +7 more
doaj   +1 more source

The Effects of Holothurin and Caspofungin on the Vaginal Cell Inflammation Parameters of the Rattus norvegicus Strain Post Induction of Candida albicans

Infection and Drug Resistance, 2023
Sri Handayani,1,2 Nurdiana Nurdiana,3 Sri Winarsih,4 Agustina Tri Endharti5 1Doctoral Program of Medical Science Department, Faculty of Medicine, Brawijaya University, Malang, Indonesia; 2Department of Midwifery of Aisyiyah, Institution of Surakarta ...
Handayani S, Nurdiana N, Winarsih S, Tri Endharti A   +3 more
doaj  

Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents [PDF]

, 2013
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive.
Leonardi, Darío, Spampinato, Claudia Patricia   +1 more
core   +3 more sources

Development and Quality Control of a Population Pharmacokinetic Model Library for Caspofungin

Pharmaceutics
Background: Caspofungin is an echinocandin antifungal agent commonly used as the first-line therapy for invasive candidiasis, salvage therapy for invasive aspergillosis, and empirical therapy for presumed fungal infections.
Nuo Xu, Yufei Shi, Yixue Wang, Wenyao Mak, Wenyu Yang, Kar Weng Ng, Yue Wu, Zhijia Tang, Qingfeng He, Gangfeng Yan, Xiaoqiang Xiang, Xiao Zhu   +11 more
doaj   +1 more source

The Effect of the Echinocandin Analogue Caspofungin on Cell Wall Glucan Synthesis byCryptococcus neoformans [PDF]

, 2000
Marta Feldmesser, Yvonne Kress, Aron Mednick, Arturo Casadevall   +3 more
openalex   +1 more source

Correlation between Antifungal Susceptibilities of Coccidioides immitis In Vitro and Antifungal Treatment with Caspofungin in a Mouse Model [PDF]

, 2001
Gloria M. González, Rolando Tijerina, Laura K. Najvar, Rosie Bocanegra, Michael Luther, Michael G. Rinaldi, John R. Graybill   +6 more
openalex   +1 more source