Results 71 to 80 of about 25,252 (242)

Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance [PDF]

, 2014
Clinical echinocandin resistance among Candida glabrata strains is increasing, especially in the United States. Antifungal susceptibility testing is considered mandatory to guide therapeutic decisions.
Afeltra, Javier, Dudiuk, Catiana Beatriz, Gamarra, Maria Soledad, Garcia, Guillermo Manuel, Jimenez Ortigoza, Cristina, Leonardelli, Florencia, Perlin, David S., Vitale, Roxana Gabriela   +7 more
core   +2 more sources

Candida auris in Heart Transplant Donor: First Isolation in a Southern Italy Heart Transplant Center

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of infection control in a heart transplant from a donor colonized with Candida auris: from detection at retrieval to strict isolation, antifungal prophylaxis, negative follow‐up cultures, and successful prevention of transmission. ABSTRACT Candida auris is an emerging multidrug‐resistant fungal pathogen increasingly implicated in healthcare ...
Lorenzo Giovannico, Giuseppe Fischetti, Luca Savino, Giuseppina Caggiano, Maria Chironna, Silvio Tafuri, Tomaso Bottio   +6 more
wiley   +1 more source

Drug-Resistant Candida glabrata Infection in Cancer Patients

Emerging Infectious Diseases, 2014
Cancer patients are at risk for candidemia, and increasing Candida spp. resistance poses an emerging threat. We determined rates of antifungal drug resistance, identified factors associated with resistance, and investigated the correlation between ...
Dimitrios Farmakiotis, Jeffrey J. Tarrand, Dimitrios P. Kontoyiannis   +2 more
doaj   +1 more source

Targeted Therapy of Fungal Keratitis Enabled by Iron Nutritional Deprivation Combined With Photothermal Effect

Small Structures, Volume 7, Issue 1, January 2026.
This work developed a PDC nanoplatform that orchestrated a multimodal synergistic therapy, combining active targeting, photothermal therapy, and iron nutrient deprivation. The antifungal, anti‐inflammatory efficacy and corneal repair ability of nanoplatform were demonstrated through both in vitro and in vivo evaluations.
Ruojiao Feng, Lingshuai Meng, Shuping Zhang, Jie Zhang, Chuchu Hu, Jiaxin Zhang, Junchao Xia, Xiaoshuo Yue, Quanlin Wang, Xiaoran Liu, Wenruo Xu, Yinglun Sun, Panhong Niu, Hua Gao   +13 more
wiley   +1 more source

Successful caspofungin treatment of persistent candidemia in extreme prematurity at 23 and 24 weeks' gestation

Journal of the Formosan Medical Association, 2014
Systemic fungal infection continues to be a major cause of mortality in extremely low-birth-weight premature infants. Amphotericin B has been recommended as the primary treatment; however, its use is limited due to drug-induced nephrotoxicity and ...
Ga Won Jeon, Jong Beom Sin
doaj   +1 more source

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, Volume 208, Issue 1, Page 250-258, January 2026.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Candida albicans Cells Lacking AP‐2 Have Defective Hyphae and Are Avirulent Despite Increased Host Uptake and Intracellular Proliferation in Macrophages

Molecular Microbiology, Volume 125, Issue 1, Page 1-12, January 2026.
Mutation of exocytic cargo adapter apm4Δ/Δ results in reduced virulence of Candida albicans during infection despite promoting intracellular growth in macrophages. ABSTRACT Candida albicans is a commensal microbe and opportunistic human pathogen. Candida yeast are recognized and taken up by macrophages via phagocytosis.
Stella Christou, Shannon Evans, Harriet Knafler, Iwona Smaczynska‐de Rooij, Kathryn R. Ayscough, Simon A. Johnston   +5 more
wiley   +1 more source

Characterisation of Antifungal Prophylaxis and Therapy Among Inpatients With Haematological Malignancies in Non‐Research Clinical Setting: A Multicentre Italian Experience

Mycoses, Volume 69, Issue 1, January 2026.
ABSTRACT Background Invasive fungal infections (IFI) are a prominent cause of morbidity and mortality among patients with haematological malignancies (HMs). Diagnostic work‐up excluding IFI is mandatory in case of persistent fever while antifungal treatment (AFT) is started.
Criscuolo Marianna, Bonanni Matteo, Martino Giordana, Farina Francesca, Verga Luisa, Marchesi Francesco, Basilico Claudia, Del Principe Maria Ilaria, Tisi Maria Chiara, Cattaneo Chiara, Picardi Marco, Bonuomo Valentina, Fracchiolla Nicola, Candoni Anna, Perruccio Katia, Stanzani Marta, Cesaro Simone, Fanci Rosa, Dargenio Michela, Forghieri Fabio, Ballanti Stelvio, Cudillo Laura, Cuccaro Annarosa, Carraro Francesca, Zama Daniele, Armiento Daniele, Garzia Maria Grazia, Spolzino Angelica, Busca Alessandro, Pagano Livio   +29 more
wiley   +1 more source

A Cross‐Sectional Study to Determine Candida spp. Carriage in Libyan Patients With Type 2 Diabetes

BioMed Research International, Volume 2026, Issue 1, 2026.
The risk for Candida infections in patients with diabetes mellitus (DM) is three times higher than in the general population. Despite a DM prevalence of 15.8% reported in Libya (2024), the laboratory identification and susceptibility testing of fungal infections in patients with DM are not routinely performed.
Mustafa H. M. Esmaio, Pedro M. D. S. Abrantes, Charlene W. J. Africa, Mohsin Khurshid   +3 more
wiley   +1 more source

Asymptomatic Candiduria due to Candida inconspicua in a Patient With Hematologic Malignancy

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Candida inconspicua is an uncommon opportunistic yeast, increasingly reported in immunocompromised patients. We describe a case of asymptomatic Candiduria caused by C. inconspicua in a 43‐year‐old woman with Philadelphia chromosome‐positive B‐cell acute lymphoblastic leukemia undergoing chemotherapy.
Andrés Soto, Javier Tinoco-Cahuana, Paulo Charpentier-Videla, Edgardo Rojas-Mancilla, Diego Macias-Cofre, Daniela Caceres-Canales, Cecilia Morales-Gonzalez, Lissette Guajardo-Quileñan, Jose Luis Briones-Martinez, Esteban Mejias-Escobar, Carolina Selman-Bravo, Francisca Sanchez-Jorquera, Dawei Cui   +12 more
wiley   +1 more source