Results 51 to 60 of about 16,636 (201)
Journal of the Formosan Medical Association, 2014 Systemic fungal infection continues to be a major cause of mortality in extremely low-birth-weight premature infants. Amphotericin B has been recommended as the primary treatment; however, its use is limited due to drug-induced nephrotoxicity and ...
Ga Won Jeon, Jong Beom Sin
doaj +1 more source
Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.Naganishia diffluens, a rare non‐neoformans cryptococcal species, was identified by PCR sequencing as the causative agent of oral cryptococcosis in a 31‐year‐old Iranian man with β‐thalassemia. This case represents the first documented instance of oral infection by N.
Zahra Yahyazadeh +13 more
wiley +1 more source
Caspofungin binding to iron compromises its antifungal efficacy against Candida albicans
Communications BiologyEchinocandins, which inhibit the synthesis of β-1,3-D-glucans, essential components of the fungal cell wall, are frontline drugs for invasive fungal infections (IFIs) caused by Candida spp.
Andreia Pedras +12 more
doaj +1 more source
Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats
MicrobiologyOpen, Volume 15, Issue 3, June 2026.ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi +3 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 9, 15 May 2026.Cell wall stress in yeast triggers transcriptional reprogramming through the CWI pathway. This study identifies Sus1, a subunit of SAGA and TREX‐2, as a key regulator in this process. Sus1 associates with stress‐responsive genes, promoting pre‐initiation complex assembly, chromatin remodeling, and RNA Pol II progression independently of H2B ...
Mónica Pavón‐Vergés +4 more
wiley +1 more source
Reasons for Failure of Antifungal-lock Therapy with Caspofungin: Need for Higher Concentrations
, 2017 Antifungal-lock therapy (AfLT) has arrived as an investigational approach for preventing catheter removal with limited clinical evidence of its efficiency.
Gökhan Ceylan +7 more
core +1 more source
Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.This review focuses on vulvovaginal candidiasis (VVC), examining its epidemiology, the pathogenesis of Candida albicans, and its relationships with vaginal microbiota. It comprehensively reviews probiotic‐based management strategies and their mechanisms of action, and concludes by discussing current limitations, challenges and future research ...
Tong Chen +13 more
wiley +1 more source
MedComm, Volume 7, Issue 5, May 2026.Our pilot clinical study in laryngeal transplantation achieved divergent outcomes: two cases maintained functional speech/swallowing with around 2 year graft survival and have been ongoing, while two succumbed to sepsis (10mo) and hemorrhagic recurrence (11mo).
Zheng Jiang +9 more
wiley +1 more source
Insufficient serum caspofungin levels in a paediatric patient on ECMO [PDF]
, 2013 Caspofungin, aechinocandin, is a relatively new lipophilic antifungal drug. Little is known concerning the pharmacokinetics of caspofungin in children. Extracorporeal membrane oxygenation (ECMO) allows prolonged cardiopulmonary support in patients with ...
Wildschut, E.D. (Enno) +4 more
core +1 more source
Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta‐Analysis
International Wound Journal, Volume 23, Issue 5, May 2026.ABSTRACT Diabetic foot ulcers (DFUs) are one of the most serious and common complications that, if not treated properly, can lead to potential damage and even amputation. The aim of this systematic review and meta‐analysis was to assess the drug‐resistant Candida species in DFU.
Mohammad Hossein Ekvan +7 more
wiley +1 more source