Results 101 to 110 of about 229,451 (392)
Molecular and cellular mechanisms of castration resistant prostate cancer
With increases in the mortality rate and number of patients with prostate cancer (PCa), PCa, particularly the advanced and metastatic disease, has been the focus of a number of studies globally.
Yiqiao Huang+3 more
semanticscholar +1 more source
Stacking Interventions Enhances Carbon Removals and Profitability of Livestock Production Systems
The study indicates that stacking multiple interventions aimed at maximising soil organic carbon (SOC) sequestration and enteric methane (CH4) reductions realizes greater abatement and profit do any singular intervention, especially when SOC sequestration accounts for a significant proportion of greenhouse gas emissions (GHG) mitigation. Abstract While
My Pham‐Kieu+3 more
wiley +1 more source
Linking prostate cancer cell AR heterogeneity to distinct castration and enzalutamide responses
Expression of androgen receptor (AR) in prostate cancer (PCa) is heterogeneous but the functional significance of AR heterogeneity remains unclear. Screening ~200 castration-resistant PCa (CRPC) cores and whole-mount sections (from 89 patients) reveals 3
Qiuhui Li+24 more
semanticscholar +1 more source
This review summarizes recent advances in the spatiotemporal dynamics of the tumor microenvironment (TME). It highlights the roles of diverse immune and stromal cell populations, spatial architecture of the TME, as well as the gut and tumor microbiota in influencing responses to immune checkpoint inhibitors (ICIs), by integrating insights from single ...
Yuanyuan Zhang, Zhihua Liu
wiley +1 more source
(1) Background: It has been well established that castration and tail docking are both painful during and following the procedure, yet there are limited convenient and effective products to address both short-term and long-term pain. Lidocam Topical Gel (
Denis Nagel+7 more
doaj +1 more source
COMPARATIVE EFFECTS OF DETOMIDINE AND XYLAZINE AS SEDATIVE AND ANALGESIC AGENTS IN SMALL RUMINANTS [PDF]
The study was carried out on 60 healthy rams and male goats presented for castration in the Surgery Clinics, Department of Clinical Medicine and Surgery, University of Veterinary and Animal Sciences, Lahore.
M. A. Khan, M. Ashraf, K. Pervez, H. B. Rashid, A. K. Mahmood and M. Chaudhry1
doaj
Immunocastration (ImC) has been proposed as an animal welfare-friendly alternative to reduce sexual and aggressive behavior and to increase carcass fat deposition with positive effects on meat quality.
D.J. Brigida+9 more
doaj +1 more source
Establishment of a patient‐derived drug‐resistant oral squamous cell carcinoma animal model
Patient‐derived xenograft (PDX) tissues from less‐responsive groups (larger tumors) were serially passaged. Sequential passaging and drug exposure in PDX models recapitulated clinical tumor evolution, enabling the development of drug‐resistant oral squamous cell carcinoma (OSCC) models. This study can offer methodological insights for precision therapy
Chuanni Feng+8 more
wiley +1 more source
Pig meat quality from entire males
This paper constitutes an updated review of the production and meat quality aspects of rearing entire male pigs. Since a major obstacle in rearing entire males is the incidence of boar taint, possible methods for detection are also summarised.
K. Lundström+2 more
doaj +1 more source