Results 101 to 110 of about 86,006 (297)
Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Mass Spectrometry Reviews, EarlyView.Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
The Journal of Pathology, EarlyView.Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi +8 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Flowers can communicate reproductive status to pollinators through visual cues. In Saxifraga fortunei, pistils often changed from yellow to red after pollination, and hoverflies and honeybees preferentially visited flowers with yellow pistils. This pattern suggests that a post‐pollination color shift confined to the pistil can reduce revisits to ...
Kazuma Takizawa +2 more
wiley +1 more source
Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness
The Prostate, EarlyView.ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen +9 more
wiley +1 more source
Desde el Jardín de Freud, 2012 A partir de las elaboraciones de Freud, de Lacan y de Melman, los autores intentarán resolver las siguientes preguntas: ¿el alcoholismo es un síntoma en sí o un coadyuvante de la neurosis obsesiva? ¿Es una enfermedad o un medicamento?
María Del Socorro Tuirán Rougeon +1 more
doaj
Animal, 2015 A total of 64 intensively reared Friesian steers were used in a 2×2×2 design to study the effects of age of castration (15 days old v. 5 months old), dietary protein level (14.6% v. 16.8%; DM basis) and lysine/methionine (lys/met) ratio (3.0 v.
I.N. Prado +6 more
doaj +1 more source
Enzalutamide for the treatment of metastatic castration-resistant prostate cancer
, 2015 Alejo Rodriguez-Vida,1 Myria Galazi,1 Sarah Rudman,1 Simon Chowdhury,1 Cora N Sternberg2 1Medical Oncology Department, Guy’s and St Thomas’ NHS Foundation Trust, London, UK; 2Medical Oncology Department, San Camillo and Forlanini Hospitals ...
Galazi M +4 more
core
Smart Molecules, EarlyView.The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou +4 more
wiley +1 more source
Veterinární Medicína, 2009 The aim of this study was to determine whether serum levels of 17beta-estradiol and progesterone are significant diagnostic tools for the confirmation of specific reproductive diseases associated with hyperestrogenism.
K. Hauptman +4 more
doaj +1 more source
Re: The Role of MicroRNA in Castration-Resistant Prostate Cancer
, 2016 EDITORIAL COMMENT Castration-resistant prostate cancer (CRPC) arises when hormone refractory prostate cancer growth occurs in a castrate androgen level environment. Although the mechanism is not fully understood, the androgen receptor (AR) has emerged
Fehmi Narter
core +1 more source