BJUI Compass, Volume 4, Issue 1, Page 44-58, January 2023., 2023 Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting.
Nan Fang Wang +3 more
wiley +1 more source
Pengaruh kastrasi terhadap performan produksi Sapi Persilangan Wagyu berdasarkan umur yang berbeda
Jurnal Ilmu-Ilmu Peternakan, 2016 The purpose of this research was to know the effect of castration to Wagyu crossbreed cattle production performance based on age difference and know the appropriate age to do castration.
Kuswati Kuswati +4 more
doaj +1 more source
Oral ethinylestradiol in castration resistent prostate cancer: 10 year experience [PDF]
, 2015 To describe our 10-year experience with the use of oral ethinylestradiol in the treatment of metastatic castration-resistant prostate cancer. METHODS: From February 2000 to April 2010, 116 patients with a metastatic castration-resistant prostate cancer
Aggarwal +16 more
core +1 more source
The incidence of uterine pathology in ovariectomised bitches
Veterinary Evidence, 2020 PICO question What is the incidence of postoperative uterine pathology in ovariectomised bitches compared to ovariohysterectomised bitches? Clinical bottom line Category of research question Incidence The number and type of study ...
Maria Norell Candetoft
doaj +1 more source
Resource efficiency and economic implications of alternatives to surgical castration without anaesthesia [PDF]
, 2009 This paper presents an analysis of the economic implications of alternative methods to surgical castration without anaesthesia. Detailed research results on the economic implications of four different alternatives are reported.
Baltussen, W.H.M. +3 more
core +2 more sources
Measurement of Fecal Testosterone Metabolites in Mice: Replacement of Invasive Techniques [PDF]
, 2020 Testosterone is the main reproductive hormone in male vertebrates and conventional methods to measure testosterone rely on invasive blood sampling procedures.
Auer, Kerstin E. +5 more
core +1 more source
Divergent clonal evolution of castration resistant neuroendocrine prostate cancer
Nature Network Boston, 2016 An increasingly recognized resistance mechanism to androgen receptor (AR)-directed therapy in prostate cancer involves epithelial plasticity, in which tumor cells demonstrate low to absent AR expression and often have neuroendocrine features.
H. Beltran +18 more
semanticscholar +1 more source
Enzalutamide and Survival in Nonmetastatic, Castration-Resistant Prostate Cancer.
New England Journal of Medicine, 2020 BACKGROUND Preliminary trial results showed that enzalutamide significantly improved metastasis-free survival among men who had nonmetastatic, castration-resistant prostate cancer and rapidly increasing prostate-specific antigen (PSA) levels while taking
C. Sternberg +17 more
semanticscholar +1 more source
Prevalence and risk factors for urinary incontinence in bitches five years after ovariohysterectomy [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 Ovariohysterectomy (OHE) is the most performed elective surgery in veterinary medicine. Although this procedure brings benefits both to the animal and public health, acquired urinary incontinence is a possible complication resultant from it.
B. Leupolt +3 more
doaj +2 more sources
Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer.
New England Journal of Medicine, 2019 BACKGROUND Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared ...
K. Chi +19 more
semanticscholar +1 more source