Results 11 to 20 of about 116,620,127 (129)

CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production [PDF]

mLife
Staphylococcus aureus is a notorious opportunistic pathogen with remarkable adaptability, enabling it to infect virtually every human tissue. Staphyloxanthin (STX), a critical virulence factor, contributes to S. aureus oxidative damage.
Xian Chen, Huagang Peng, Xiancai Rao, Yi Yang, Keting Zhu, Zhen Hu, Shu Li, Xiaonan Huang, Feng Lin, Jianghong Wu, Weilong Shang, Renjie Zhou, Yifan Rao   +12 more
doaj   +3 more sources

Assessment of CcpA-mediated catabolite control of gene expression in Bacillus cereus ATCC 14579 [PDF]

BMC Microbiology, 2008
Background The catabolite control protein CcpA is a transcriptional regulator conserved in many Gram-positives, controlling the efficiency of glucose metabolism.
Buist Girbe, Kuipers Oscar P, van der Voort Menno, de Vos Willem M, Abee Tjakko   +4 more
doaj   +5 more sources

Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum

BMC Genomics, 2012
Background Clostridium acetobutylicum has been used to produce butanol in industry. Catabolite control protein A (CcpA), known to mediate carbon catabolite repression (CCR) in low GC gram-positive bacteria, has been identified and characterized in C ...
Ren Cong, Gu Yang, Wu Yan, Zhang Weiwen, Yang Chen, Yang Sheng, Jiang Weihong   +6 more
doaj   +2 more sources

Transcriptional regulation of cellobiose utilization by PRD-domain containing Sigma54-dependent transcriptional activator (CelR) and catabolite control protein A (CcpA) in Bacillus thuringiensis [PDF]

Frontiers in Microbiology
Cellobiose, a β-1,4-linked glucose dimer, is a major cellodextrin resulting from the enzymatic hydrolysis of cellulose. It is a major source of carbon for soil bacteria.
Liangwei Zhang, Hong Xu, Haijian Cheng, Fuping Song, Jie Zhang, Qi Peng   +5 more
doaj   +2 more sources

Gene regulation by CcpA and catabolite repression explored by RNA-Seq in Streptococcus mutans. [PDF]

PLoS ONE, 2013
A bacterial transcriptome of the primary etiological agent of human dental caries, Streptococcus mutans, is described here using deep RNA sequencing. Differential expression profiles of the transcriptome in the context of carbohydrate source, and of the ...
Lin Zeng, Sang Chul Choi, Charles G Danko, Adam Siepel, Michael J Stanhope, Robert A Burne   +5 more
doaj   +3 more sources

Structure of the apo form of the catabolite control protein A (CcpA) from Bacillus megaterium with a DNA-binding domain. [PDF]

Acta Crystallogr Sect F Struct Biol Cryst Commun, 2007
Crystal structure determination of catabolite control protein A (CcpA) at 2.6 A resolution reveals for the first time the structure of a full-length apo-form LacI-GalR family repressor protein. In the crystal structures of these transcription regulators,
Singh RK, Palm GJ, Panjikar S, Hinrichs W.   +3 more
europepmc   +2 more sources

CcpA-mediated regulation of cellular energy metabolism in the ruminal bacterium Streptococcus bovis [PDF]

Microbiology Spectrum
This study investigated the cellular energy metabolite profiles of Streptococcus bovis S1. Glucose concentrations of 5 or 50 mM and the presence or absence of ccpA were applied during the cultivation of S. bovis S1. Results revealed the identification of
Yunan Weng, Yaqian Jin, Wenze Zhang, Lihong Wang, Hongrong Wang   +4 more
doaj   +2 more sources

Glucose-induced active lysogeny of prophage ΦSa3XN promotes Staphylococcus aureus virulence [PDF]

Virology Journal
Background Active lysogeny is a newly characterized mechanism that the dynamic integration and excision of prophages serve as molecular switches to coordinately regulate bacterial gene expression without generating progeny virions.
Wei Huang, Xing Tian, Keting Zhu, Shuguang Lu, Yan Zhao, Jing Zhou, Tongyu He, Chao Li, Ming Li, Renjie Zhou, Gang Li   +10 more
doaj   +2 more sources

Promoting cytidine biosynthesis by modulating pyrimidine metabolism and carbon metabolic regulatory networks in Bacillus subtilis [PDF]

Microbial Cell Factories
Background The modification of single or multiple genes via metabolic engineering can lead to the dysregulation of central metabolism and affect bacterial growth and metabolite accumulation.
Xiangjun Zhang, Lu Liu, Pilian Niu, Tong Ye, Wei Ding, Xiaobo Wei, Junnan Xu, Haitian Fang, Huiyan Liu   +8 more
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The ABC type fucose operon regulated by XtrSs through CcpA contributes to Streptococcus suis survival in macrophages [PDF]

Virulence
Streptococcus suis (S. suis), an important zoonotic pathogen, poses a huge threat to the pig industry and human health. The fucose operon (FCS) is found in many bacteria that utilize host glycosylation modifications, contributing to bacterial growth and ...
Song Liang, Yumin Zhang, Shidan Zhang, Qiankun Bai, Xinming Pan, Jianan Liu, Qibing Gu, Huochun Yao, Guangjin Liu   +8 more
doaj   +2 more sources